Results 61 to 70 of about 199,378 (307)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
CoRR, 2017 We prove that if a group generated by a bireversible Mealy automaton contains an element of infinite order, its growth blows up and is necessarily exponential. As a direct consequence, no infinite virtually nilpotent group can be generated by a bireversible Mealy automaton.
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Gramatyka nieskończoności. Ludwiga Wittgensteina krytyka teorii mnogości
Analiza i Egzystencja, 2023 The paper discusses a relatively underexamined element of Wittgenstein’s philosophy of mathematics associated with his critique of set theory. I outline Wittgenstein’s objections to the theories of Dedekind and Cantor, including the confounding of ...
Piotr Dehnel
doaj +1 more source
, 2023 This work starts from definition of randomness, the results of algorithmic randomness are analyzed from the perspective of application. Then, the source and nature of randomness is explored, and the relationship between infinity and randomness is found.
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Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source
Beyond Bounds: Infinity in Cavendish’s Ontology
Journal of Modern PhilosophyMargaret Cavendish endorses the view that matter is actually infinite. This paper offers a systematic treatment of Cavendish’s views on infinity as developed in her later philosophical works (roughly, from Philosophical Letters onwards).
Laura Georgescu
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Proceedings of the American Mathematical Society, 1976 This paper formalizes Gödel’s 1946 conjecture that every set-theoretic sentence is decidable from the present axioms plus some true axioms of infinity; and we prove a weak variant of this conjecture to be true for every
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International Journal of Adaptive Control and Signal Processing, EarlyView.This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir +2 more
wiley +1 more source