Results 21 to 30 of about 87,723 (231)

Embodiment of infinity in mathematics

open access: yesFrontiers in Psychology
In this article, we discuss the embodiment of infinity as one of fundamental concepts in mathematics. In contrast to the embodiment of many other mathematical concepts, the embodiment of infinity is an endless dynamic process.
Omid Khatin-Zadeh   +2 more
doaj   +1 more source

What in the World is Universe? : A Prime Example [PDF]

open access: yesФилософия и космология, 2016
This writing attempts to capture mind and matter to rational description by focusing on disparity between scientific method as it extracts concepts and discards particulars and ordinary cognitive functioning that extends from proximal experience ...
Marvin E. Kirsh
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Fine-tuning levels of filamins a and b as a specific mechanism sustaining Th2 lymphocyte functions

open access: yesNature Communications
Augmenting the portfolio of therapeutics for type 2-driven diseases is crucial to address unmet clinical needs and to design personalized treatment schemes. An attractive therapy for such diseases would consist in targeting the recruitment of T helper 2 (
Kilian Maire   +16 more
doaj   +1 more source

Descartes, the Metaphysics and the Infinite

open access: yesLexicon Philosophicum
Divine infinity in the Cartesian corpus can be diffracted into an infinity of distance, proper to the creation of eternal truths (1630), and an infinity of substance, identifiable in Meditatio III (1641).
Dan Arbib
doaj   +1 more source

Mehmed Emīn Üsküdarī’s Sharh al-Barahīn al-khamsa on Infinity [PDF]

open access: yesNazariyat: Journal for the History of Islamic Philosophy and Sciences, 2022
This article examines the form and content of Sharh al-Barāhīn al-khamsa, written by Mehmed Emīn Üsküdārī (d. 1149/1736-37), an important figure of eighteenth-century Ottoman Turkish philosophical thought, on the problems of the finitude of extensions ...
M. Necmeddin Beşikci
doaj  

Assessing risk of damage to posterior ankle structures during total ankle arthroplasty

open access: yesBone & Joint Open, 2021
Aims: Arthroplasty has become increasingly popular to treat end-stage ankle arthritis. Iatrogenic posterior neurovascular and tendinous injury have been described from saw cuts. However, it is hypothesized that posterior ankle structures could be damaged
Christopher J. Callaghan   +1 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

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