Results 1 to 10 of about 50 (47)
The past few years of research on leptin have provided important information on the link between metabolism and immune homeostasis. Adipocytes influence not only the endocrine system but also the immune response through several cytokine-like mediators known as adipokines, which include leptin.
Iikuni N+4 more
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Sphingolipids in Inflammation [PDF]
The etiology of many diseases results from the dysregulation of inflammation. Understanding the molecular mechanisms controlling the inflammatory response is essential to formulate therapeutic strategies for the treatment of inflammatory conditions. In fact, substantial research has unveiled important aspects of the inflammatory machinery, both at the ...
Elisabetta Albi+2 more
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In the article the characteristic of ethiology and key parts of pathogenesis of inflammation is given; modern data on the role of adhesive molecules, active forms of oxygen, lipoperoxidation processes, cytokines and other mediators in the development of acute and chronic inflammation are analyzed; the principles of its treatment are substantiated.Key ...
Elgazzar, Abdelhamid H.+1 more
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Cachexia is a complex wasting syndrome associated with a marked detrimental effect upon life quality and survival in patients with cancer, chronic obstructive pulmonary disease (COPD), chronic heart failure, AIDS, and chronic kidney disease, among other conditions. Its prevalence is of around 5 to 15% in cardiac patients at end stage, rising up to 30%,
Seelaender M.+5 more
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Nanoparticles and Inflammation [PDF]
The development of nanoscale molecular probes capable of diagnosis, characterization, and clinical treatment of disease is leading to a new generation of imaging technologies. Such probes are particularly relevant to inflammation, where the detection of subclinical, early disease states could facilitate speedier detection that could yield enhanced ...
Axel J. Hueber+5 more
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Inflammation and Atherosclerosis [PDF]
The aim of this article is to discuss the role of inflammation in atherosclerosis.An initial chemical, mechanical or immunological insult induces endothelial dysfunction. This triggers a cascade of inflammatory reactions, in which monocytes, macrophages, T lymphocytes and vascular smooth muscle cells participate. Leukocyte adhesion molecules, cytokines,
Kaperonis, EA+4 more
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Exercise and Inflammation [PDF]
Exercise and inflammation induce multi-faceted physiological responses in their own right, let alone when considered together [...]
Llion Roberts, Katsuhiko Suzuki
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Inflammation and haemostasis are interrelated pathophysiologic processes that considerably affect each other. In this bidirectional relationship, inflammation leads to activation of the haemostatic system that in turn also considerably influences inflammatory activity.
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Autophagy and inflammation [PDF]
AbstractAutophagy is a homeostatic mechanism involved in the disposal of damaged organelles, denatured proteins as well as invaded pathogens through a lysosomal degradation pathway. Recently, increasing evidences have demonstrated its role in both innate and adaptive immunity, and thereby influence the pathogenesis of inflammatory diseases.
Xiangdong Wang+2 more
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