Results 1 to 10 of about 3,845,409 (411)
Systemic inflammation predicts all-cause mortality: a Glasgow Inflammation Outcome Study [PDF]
, 2015 Introduction: Markers of the systemic inflammatory response, including C-reactive protein and albumin (combined to form the modified Glasgow Prognostic Score), as well as neutrophil, lymphocyte and platelet counts have been shown to be prognostic of ...
Fletcher, Colin D. +5 more
core +10 more sources
Current Immunology Reviews, 2008 The past few years of research on leptin have provided important information on the link between metabolism and immune homeostasis. Adipocytes influence not only the endocrine system but also the immune response through several cytokine-like mediators known as adipokines, which include leptin.
Iikuni N +4 more
openaire +6 more sources
OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
Cell Death and Disease, 2023 The intestinal epithelium is a single cell layer that is constantly renewed and acts as a physical barrier that separates intestinal microbiota from underlying tissues.
Lien Verboom +10 more
doaj +1 more source
Cell Death and Disease, 2023 Plasma membrane permeabilization (PMP) is a defining feature of regulated necrosis. It allows the extracellular release of damage-associated molecular patterns (DAMPs) that trigger sterile inflammation. The pore forming molecules MLKL and GSDMs drive PMP
Yves Dondelinger +5 more
doaj +1 more source
Inflammation in benign prostate tissue and prostate cancer in the finasteride arm of the Prostate Cancer Prevention Trial [PDF]
, 2016 BACKGROUND: A previous analysis of the placebo arm of the Prostate Cancer Prevention Trial (PCPT) reported 82% overall prevalence of intraprostatic inflammation and identified a link between inflammation and higher-grade prostate cancer and serum PSA ...
Barber, John R +15 more
core +2 more sources
Вопросы современной педиатрии, 2006 In the article the characteristic of ethiology and key parts of pathogenesis of inflammation is given; modern data on the role of adhesive molecules, active forms of oxygen, lipoperoxidation processes, cytokines and other mediators in the development of acute and chronic inflammation are analyzed; the principles of its treatment are substantiated.Key ...
Elgazzar, Abdelhamid H. +1 more
openaire +10 more sources
Scientific Reports, 2023 A20 serves as a critical brake on NF-κB-dependent inflammation. In humans, polymorphisms in or near the TNFAIP3/A20 gene have been linked to various inflammatory disorders, including systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA ...
Karel F. A. Van Damme +17 more
doaj +1 more source
Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer\u27s disease [PDF]
, 2019 Interest in understanding the roles of white matter (WM) inflammation and damage in the pathophysiology of Alzheimer disease (AD) has been growing significantly in recent years.
Ances, Beau M +14 more
core +2 more sources
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity
Nature Communications, 2021 OTULIN is a deubiquitinase for linear ubiquitin chains. Here the authors show, using genetic mouse models and single-cell RNA-sequencing, that deficiency of OTULIN in keratinocytes causes skin inflammation and verrucous carcinoma via the induction of ...
Esther Hoste +16 more
doaj +1 more source
A Holistic Approach on Smart Garment for Patients with Juvenile Idiopathic Arthritis [PDF]
10.3390/engproc2023059083;2023, 2023 Juvenile Idiopathic Arthritis (JIA) is a widespread and chronic condition that affects children and adolescents worldwide. The person suffering from JIA is characterized by chronic joint inflammation leading to pain, swelling, stiffness, and limited body movements. Individuals suffering from JIA require ongoing treatment for their lifetime.
arxiv +1 more source