Results 141 to 150 of about 4,758,008 (341)

Malnutrition and inflammation in peritoneal dialysis patients [PDF]

, 2003
Paul A. Fein, Neal Mittman, Rajdeep Gadh, Jyotiprakas Chattopadhyay, Daniel A. Blaustein, Robert Mushnick, Morrell M. Avram   +6 more
openalex   +1 more source

Inflammation in obesity, diabetes, and related disorders.

Immunity, 2022
Theresa Rohm, Daniel T. Meier, J. Olefsky, M. Donath   +3 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Scavenger Receptor BI Attenuates IL-17A–Dependent Neutrophilic Inflammation in Asthma

, 2021
Sky W. Reece, Sanjay Varikuti, Brita Kilburg‐Basnyat, Katelyn Dunigan, Myles X. Hodge, Bin Luo, Jennifer H. Madenspacher, Seddon Y. Thomas, Debra A. Tokarz, Robert M. Tighe, Donald N. Cook, Michael B. Fessler, Kymberly M. Gowdy   +12 more
openalex   +2 more sources

Chronic inflammation in the etiology of disease across the life span

Nature Network Boston, 2019
David Furman, J. Campisi, E. Verdin, Pedro Carrera-Bastos, S. Targ, C. Franceschi, L. Ferrucci, D. Gilroy, A. Fasano, G. Miller, Andrew H. Miller, A. Mantovani, C. Weyand, N. Barzilai, J. Goronzy, T. Rando, R. Effros, A. Lucia, N. Kleinstreuer, George M. Slavich   +19 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

2-carba cyclic phosphatidic acid suppresses inflammation via regulation of microglial polarisation in the stab-wounded mouse cerebral cortex [PDF]

, 2018
Kei Hashimoto, Mari Nakashima, Ayana Hamano, Mari Gotoh, Hiroko Ikeshima‐Kataoka, Kimiko Murakami‐Murofushi, Yasunori Miyamoto   +6 more
openalex   +1 more source

Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal. [PDF]

, 2019
Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying ...
Christian, Parul, Cole, Robert N, Eroglu, Abdulkerim, Groopman, John, Lee, Sun Eun, Schulze, Kerry, Stewart, Christine P, West, Keith P, Wu, Lee S-F, Yager, James D   +9 more
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source