Results 161 to 170 of about 2,081,675 (219)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The inflammatory storm: Targeting residual risk in combined ASCVD and CKD. [PDF]

Am Heart J Plus
Mohandas R, Dass B, Ejaz AA.
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

From inflammation to fibrosis and cancer: the emerging role of AIEC-derived metabolites in intestinal disease progression. [PDF]

Exp Mol Med
Ahn JH, Hazelton A, Nguyen J, Arthur JC.
europepmc   +1 more source

MicroRNA-155 at the crossroads of inflammation and vascular dysfunction in essential hypertension. [PDF]

Mol Biol Rep
Salamt N, Che Roos NA, Mohamed Shakrin NNS, Ugusman A.   +3 more
europepmc   +1 more source

Systemic inflammatory biomarkers and their partial role in the association between diabetes and sarcopenia: A population-based study using NHANES data. [PDF]

Medicine (Baltimore)
Qin J, Qiu X, Liang B, Chen Y, Jiang T.
europepmc   +1 more source

Viral dsRNA triggers human fetal membrane miR-146a-3p to be packaged into small extracellular vesicles which in turn drives inflammation through activation of Toll-like Receptor 7 and 8. [PDF]

PLoS One
Georges HM, Fischer AC, Casanova P, Abrahams VM.   +3 more
europepmc   +1 more source