Results 91 to 100 of about 1,237,469 (299)

In Vitro Induction of Eryptosis by Uremic Toxins and Inflammation Mediators in Healthy Red Blood Cells. [PDF]

J Clin Med, 2022
Virzì GM, Mattiotti M, Clementi A, Milan Manani S, Battaglia GG, Ronco C, Zanella M.   +6 more
europepmc   +1 more source

Lipid mediators and inflammation leading to insulin resistance and type 11 diabetes

, 2010
Clinical and epidemiological studies suggest that patients who are overweight or obese are at greater risk to develop glucose intolerance and insulin resistance leading to type II diabetes and cardiovascular disease.
Lindsay Brown, Brown, Lindsay, Abishek Iyer, Iyer, Abishek   +3 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Nitric oxide in acute and chronic inflammation. [PDF]

, 2002
PhDNitric oxide (NO) is a signalling molecule formed when L-arginine is converted to L-citrulline by the enzyme NO synthase (NOS. NOS exists as three isoforms, ecNOS is constitutively expressed in endothelial cells and nNOS in neuronal cells, while a ...
Paul-Clark, Mark John
core   +2 more sources

Accelerated brain aging with opioid misuse and HIV: New insights on the role of glially derived pro-inflammation mediators and neuronal chloride homeostasis. [PDF]

Curr Opin Neurobiol, 2023
Hauser KF, Ohene-Nyako M, Knapp PE.
europepmc   +1 more source

Breast Cancer Associated Metastasis is Significantly Increased in a Model of Autoimmune Arthritis [PDF]

, 2008
Chronic inflammation is known to play a role in cancer initiation, promotion,and metastasis. However, the mechanism by which inflammation promotes metastasis is still unclear.
Latha Pathangey, Pinku Mukherjee, Teresa Tinder, Lopamudra Das Roy   +3 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Retracted: Neuropilin-1highCD4+CD25+ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

Mediators of Inflammation, 2020
Mediators of Inflammation
doaj   +1 more source

Circulating Inflammatory Mediators and Genetic Polymorphisms of Inflammation Mediators and Their Association with Factors Related to Abdominal Aortic Aneurysm: A Systemic Review and Meta-Analysis. [PDF]

Rev Cardiovasc Med, 2022
Wang H, Zhong Z, Jiang D, Zhang H, Yin F, Guo P, Chen J, Zhu X, You K, Han Y, Liu K.   +10 more
europepmc   +1 more source

Effects of resveratrol in ınflammatory arthritis

, 2007
Inflammation, Vol. 30, Nos. 1Y2, April 2007 ( 2006)Summary: Nuclear factor kappa B (NF-kB), is a pivotal transcription factor involved in the activation of the TNF-a and IL-1b genes.
Baysal, Özlem, Esenkaya, İrfan, Mızrak, Bülent, Elmalı, Nurzat, Harma, Ahmet   +4 more
core   +1 more source