Results 211 to 220 of about 385,011 (236)
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Tissue factor mediates inflammation
Archives of Biochemistry and Biophysics, 2005The role of tissue factor (TF) in inflammation is mediated by blood coagulation. TF initiates the extrinsic blood coagulation that proceeds as an extracellular signaling cascade by a series of active serine proteases: FVIIa, FXa, and thrombin (FIIa) for fibrin clot production in the presence of phospholipids and Ca2+. TF upregulation resulting from its
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Mitochondrial Fission Mediates Endothelial Inflammation
Hypertension, 2020Endothelial inflammation and mitochondrial dysfunction have been implicated in cardiovascular diseases, yet, a unifying mechanism tying them together remains limited. Mitochondrial dysfunction is frequently associated with mitochondrial fission/fragmentation mediated by the GTPase Drp1 (dynamin-related protein 1).
Steven J, Forrester +14 more
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Prostaglandins: Mediators of Inflammation?
Science, 1972Because the inflammatory process is complex its biochemistry is not yet well understood. Allergic reactions are actually harmful manifestations of the immune response causing inflammation in the affected part of the body. PGs (prostaglandins) have been implicated in the inflammatory and allergic reactions. Researchers however disagree on the precise
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2018
Inflammation is a physiologic response against noxious stimuli and microbial invaders. The basic elements of inflammation include host cells, blood vessels, proteins and lipid mediators, which work together to eliminate the inflammatory stimulus as well as initiate the resolution and repair.
Izabela Galvão +4 more
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Inflammation is a physiologic response against noxious stimuli and microbial invaders. The basic elements of inflammation include host cells, blood vessels, proteins and lipid mediators, which work together to eliminate the inflammatory stimulus as well as initiate the resolution and repair.
Izabela Galvão +4 more
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Mediators of Inflammation and Fibrosis
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 2007During peritoneal dialysis, peritoneal cells are repeatedly exposed to a non-physiologic hypertonic environment with high glucose content and low pH. Current sterile dialysis solutions cause inflammation in the submesothelial compact zone, leading to fibrosis, angiogenesis, and, eventually, ultrafiltration failure.
Kar Neng, Lai +2 more
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Mediators of Inflammation and Regeneration
Advances in Dental Research, 2011Characterization of the molecular response under caries lesions requires a robust and reliable transcript isolation system, and analysis of data indicated that collection of extracted teeth in either liquid nitrogen/RNA-stabilizing solution facilitated this.
P R, Cooper +4 more
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Mediators of Injury and Inflammation
World Journal of Surgery, 1996AbstractMediators play a key role in the development of systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome, and multiple organ failure of vital organs. In this short review, we update our knowledge on these mediator networks.
G, Schlag, H, Redl
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Platelets as Mediators of Inflammation
Hematology/Oncology Clinics of North America, 2007An expanding body of evidence continues to build on the central role of inflammation in the progression and clinical manifestations of atherosclerosis. Platelets, long thought to play only a reactionary role at the time of endothelial disruption, are now recognized as important mediators of the inflammatory process.
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Cytokine mediators of renal inflammation
Current Opinion in Nephrology and Hypertension, 1994This review focuses on the role of two cytokines, platelet-derived growth factor and transforming growth factor-beta, in glomerular injury. The most recent in vitro and in vivo evidence for the role of platelet-derived growth factor and transforming growth factor-beta in glomerular hypercellularity and matrix expansion is summarized.
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