Results 221 to 230 of about 400,573 (260)
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Leukotrienes as mediators of skin inflammation

British Journal of Dermatology, 2006
Leukotrienes (LTs) derived from the 5-lipoxygenase pathways of arachidonic acid metabolism, are a new group of biologically active mediators. LTC4, LTD4 and LTE4 are considered collectively to account for the activity of slow reacting substance of anaphylaxis (SRS-A). They have potent smooth muscle contracting activity (Drazen et al., 1980; Holme et al.
A W, Ford-Hutchinson, A, Rackman
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Neurokinin mediation of edema and inflammation

Neuropeptides, 2000
The aim of this article is to furnish a brief review of the role played by neurokinins in the inflammatory process. Further attention is given to the mechanisms, as well as to the receptor subtypes involved in neurokinin-mediated inflammation, in an attempt to clarify the participation of neurokinins in different models of acute and chronic ...
M M, Campos, J B, Calixto
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Mediators of inflammation and the inflammatory process

Journal of Allergy and Clinical Immunology, 1999
A complex interplay of inflammatory cells and chemical mediators is responsible for allergic inflammation. It is now understood that the allergic reaction consists of an early-phase response involving mast cell degranulation with the release of histamine and a late-phase response characterized by the migration of inflammatory cells.
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Mediators of Inflammation

Annual Review of Immunology, 1983
G L, Larsen, P M, Henson
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Cytokine Mediators of Immunity and Inflammation

Archives of Surgery, 1993
The remarkable advances in molecular and cell biology occurring over the past four decades have served the cause of surgical science well. Our understanding of basic disease mechanisms and insights into potential new therapeutic strategies have occurred at a staggering pace.
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Mediators of Inflammation

1974
1. The Mediators of Inflammation.- 2. Mechanisms Common to Several Mediator Systems.- 2.1. Cellular Release.- 2.2. Fluid-Phase Activation.- 2.3. Bypass Mechanisms.- 2.4. Extracellular Control Loops.- 2.5. Intracellular Controls.- 3. Centrality of Phagocytes.- 4. References.- 1 Mechanisms of Mediator Release from Inflammatory cells.- 1. Introduction.- 2.
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Cationic antigens as mediators of inflammation

APMIS, 1991
Electrical charge is an important determinant of antigen deposition in tissue. Cationic antigens can bind to anionic sites found in many organs. The major focus of interest has been the renal glomerulus and the articular joint. Experimental models of immune complex glomerulonephritis and allergic arthritis were established with chemically cationized ...
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Bacterial Mediated Gastrointestinal Inflammation

2013
Mouse models have proven to be a key approach in our understanding of the etiology and physiology underlying bacterial mediated gastrointestinal inflammation. Generally, these models are based on the inoculation of genetically susceptible mice with either commensal or pathogenic bacteria to elicit an inflammatory response.
Joshua, Uronis, Xiaolun, Sun
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Mediators of inflammation

Seminars in Arthritis and Rheumatism, 1985
T L, Moore, T D, Weiss
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Mediators of mucosal inflammation: implications for therapy.

Scandinavian journal of gastroenterology. Supplement, 1997
Treatment of inflammatory bowel disease remains a challenge. The major shortcoming in the development of new therapeutic approaches is the fact that the cause of inflammatory bowel disease is still unknown. Recognition of the importance of the arachidonic acid cascade of inflammatory mediators presents the opportunity to specifically inhibit or ...
VanDullemen, H   +4 more
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