Results 221 to 230 of about 400,573 (260)
Some of the next articles are maybe not open access.
Leukotrienes as mediators of skin inflammation
British Journal of Dermatology, 2006Leukotrienes (LTs) derived from the 5-lipoxygenase pathways of arachidonic acid metabolism, are a new group of biologically active mediators. LTC4, LTD4 and LTE4 are considered collectively to account for the activity of slow reacting substance of anaphylaxis (SRS-A). They have potent smooth muscle contracting activity (Drazen et al., 1980; Holme et al.
A W, Ford-Hutchinson, A, Rackman
openaire +2 more sources
Neurokinin mediation of edema and inflammation
Neuropeptides, 2000The aim of this article is to furnish a brief review of the role played by neurokinins in the inflammatory process. Further attention is given to the mechanisms, as well as to the receptor subtypes involved in neurokinin-mediated inflammation, in an attempt to clarify the participation of neurokinins in different models of acute and chronic ...
M M, Campos, J B, Calixto
openaire +2 more sources
Mediators of inflammation and the inflammatory process
Journal of Allergy and Clinical Immunology, 1999A complex interplay of inflammatory cells and chemical mediators is responsible for allergic inflammation. It is now understood that the allergic reaction consists of an early-phase response involving mast cell degranulation with the release of histamine and a late-phase response characterized by the migration of inflammatory cells.
openaire +2 more sources
Cytokine Mediators of Immunity and Inflammation
Archives of Surgery, 1993The remarkable advances in molecular and cell biology occurring over the past four decades have served the cause of surgical science well. Our understanding of basic disease mechanisms and insights into potential new therapeutic strategies have occurred at a staggering pace.
openaire +2 more sources
1974
1. The Mediators of Inflammation.- 2. Mechanisms Common to Several Mediator Systems.- 2.1. Cellular Release.- 2.2. Fluid-Phase Activation.- 2.3. Bypass Mechanisms.- 2.4. Extracellular Control Loops.- 2.5. Intracellular Controls.- 3. Centrality of Phagocytes.- 4. References.- 1 Mechanisms of Mediator Release from Inflammatory cells.- 1. Introduction.- 2.
openaire +1 more source
1. The Mediators of Inflammation.- 2. Mechanisms Common to Several Mediator Systems.- 2.1. Cellular Release.- 2.2. Fluid-Phase Activation.- 2.3. Bypass Mechanisms.- 2.4. Extracellular Control Loops.- 2.5. Intracellular Controls.- 3. Centrality of Phagocytes.- 4. References.- 1 Mechanisms of Mediator Release from Inflammatory cells.- 1. Introduction.- 2.
openaire +1 more source
Cationic antigens as mediators of inflammation
APMIS, 1991Electrical charge is an important determinant of antigen deposition in tissue. Cationic antigens can bind to anionic sites found in many organs. The major focus of interest has been the renal glomerulus and the articular joint. Experimental models of immune complex glomerulonephritis and allergic arthritis were established with chemically cationized ...
openaire +2 more sources
Bacterial Mediated Gastrointestinal Inflammation
2013Mouse models have proven to be a key approach in our understanding of the etiology and physiology underlying bacterial mediated gastrointestinal inflammation. Generally, these models are based on the inoculation of genetically susceptible mice with either commensal or pathogenic bacteria to elicit an inflammatory response.
Joshua, Uronis, Xiaolun, Sun
openaire +2 more sources
Mediators of mucosal inflammation: implications for therapy.
Scandinavian journal of gastroenterology. Supplement, 1997Treatment of inflammatory bowel disease remains a challenge. The major shortcoming in the development of new therapeutic approaches is the fact that the cause of inflammatory bowel disease is still unknown. Recognition of the importance of the arachidonic acid cascade of inflammatory mediators presents the opportunity to specifically inhibit or ...
VanDullemen, H +4 more
openaire +2 more sources

