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Mediators of Inflammation

Archives of Dermatology, 1966
THIS BRIEF review will cover only some of the important aspects of the subject but will try to define an outline from which one can gain a reasonable concept of current knowledge and proceed to further detailed investigation if he desires. One is also directed to recent detailed reviews 1-3 which should be of considerable interest.
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Prostaglandins: Mediators of Inflammation?

Science, 1972
Because the inflammatory process is complex its biochemistry is not yet well understood. Allergic reactions are actually harmful manifestations of the immune response causing inflammation in the affected part of the body. PGs (prostaglandins) have been implicated in the inflammatory and allergic reactions. Researchers however disagree on the precise
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Platelets as Mediators of Inflammation

Hematology/Oncology Clinics of North America, 2007
An expanding body of evidence continues to build on the central role of inflammation in the progression and clinical manifestations of atherosclerosis. Platelets, long thought to play only a reactionary role at the time of endothelial disruption, are now recognized as important mediators of the inflammatory process.
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Lipid Mediators of Inflammation

Rheumatic Disease Clinics of North America, 1987
Many mediators of inflammation are derived from phospholipids and polyunsaturated fatty acids, including prostaglandins, leukotrienes, and platelet-activating factor. These mediators augment the vascular phase of inflammation and modify functions of inflammatory cells and cells of the immune system.
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Mediators of Inflammation

2018
Inflammation is a physiologic response against noxious stimuli and microbial invaders. The basic elements of inflammation include host cells, blood vessels, proteins and lipid mediators, which work together to eliminate the inflammatory stimulus as well as initiate the resolution and repair.
Izabela Galvão   +4 more
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Mediators of Anaphylaxis and Inflammation

Annual Review of Microbiology, 1982
INTRODUCTION .. . . .. .. .. . .. .. .. .. .... .. .. . .. .... . .. .. . ....... .. .. ... .. . .... . .. .. . .. . .. . .. .... . .. . .. .... ... ... . . .. ..... .. 371 Release of Mediators of Anaphylaxis ... ..... .. ....... . .. .. ..... 372 Substances Considered in this Review 373 MAST CELL-DERIVED PREFORMED MEDIATORS .. . . . .. . .. ..
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Neurokinin mediation of edema and inflammation

Neuropeptides, 2000
The aim of this article is to furnish a brief review of the role played by neurokinins in the inflammatory process. Further attention is given to the mechanisms, as well as to the receptor subtypes involved in neurokinin-mediated inflammation, in an attempt to clarify the participation of neurokinins in different models of acute and chronic ...
M M, Campos, J B, Calixto
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Inflammation Mediators and the Inflammatory Reaction

Archives of Dermatology, 1964
A technique is described whereby the keratin layer of the skin is removed by stripping and the inflamed porous site is pretreated with inflammatory and antiinflammatory agents. Fluorescein and sodium anazolene (Coomassie Blue) are used as indicators of capillary permeability.
L, FRANK   +3 more
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Bacterial Mediated Gastrointestinal Inflammation

2013
Mouse models have proven to be a key approach in our understanding of the etiology and physiology underlying bacterial mediated gastrointestinal inflammation. Generally, these models are based on the inoculation of genetically susceptible mice with either commensal or pathogenic bacteria to elicit an inflammatory response.
Joshua, Uronis, Xiaolun, Sun
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PGI2: A potential mediator of inflammation

Prostaglandins, 1978
PGI2, but not its metabolite 6oxoPGF1alpha, is equivalent in potency to PGE1 as a potentiator of carrageenan, histamine and bradykinin-induced rat paw oedemas. PGI2 must, therefore, be considered as a potential mediator of inflammatory processes.
A W, Ford-Hutchinson   +3 more
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