Results 271 to 280 of about 362,551 (290)
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Neurokinin mediation of edema and inflammation
Neuropeptides, 2000The aim of this article is to furnish a brief review of the role played by neurokinins in the inflammatory process. Further attention is given to the mechanisms, as well as to the receptor subtypes involved in neurokinin-mediated inflammation, in an attempt to clarify the participation of neurokinins in different models of acute and chronic ...
João B. Calixto, Maria M. Campos
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Lipid Mediators of Inflammation
2001Inflammatory processes are the response of the organism to potentially harmful stimuli, such as infection, trauma, and immunological events. The inflammatory reaction is characterized by the release of a variety of inflammatory mediators and modulators that alter microvascular functions and govern leukocyte recruitment and extravasation of plasma ...
Lennart Lindbom, Per Hedqvist
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Bacterial Mediated Gastrointestinal Inflammation
2013Mouse models have proven to be a key approach in our understanding of the etiology and physiology underlying bacterial mediated gastrointestinal inflammation. Generally, these models are based on the inoculation of genetically susceptible mice with either commensal or pathogenic bacteria to elicit an inflammatory response.
Xiaolun Sun, Joshua M. Uronis
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Mediators of inflammation and the inflammatory process
Journal of Allergy and Clinical Immunology, 1999A complex interplay of inflammatory cells and chemical mediators is responsible for allergic inflammation. It is now understood that the allergic reaction consists of an early-phase response involving mast cell degranulation with the release of histamine and a late-phase response characterized by the migration of inflammatory cells.
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Mediators of Vascular Inflammation
2011Inflammation is a basic pathological mechanism that underlies a variety of diseases. The inflammatory reaction involves the complex interactions between inflammatory cells (neutrophils, lymphocytes and monocytes/macrophages) and vascular cells (endothelial [EC] and smooth muscle cells [SMC]).
Ziad Mallat +5 more
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Update on Histamine as a Mediator of Inflammation
Allergy and Asthma Proceedings, 2000Histamine is an important mediator and regulator of inflammation. Histamine acts via H1, H2, and H3 receptors that are functionally coupled to G-proteins and histamine release is regulated by cytokines that act as histamine release factors. Histamine suppresses the immune response and deviates the immune response toward the Th2 pathway.
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Lipid Mediators and Inflammation
1986The role of arachidonic metabolites in the control of immunity in inflammation is reviewed with particular emphasis on the most recent observations and possible interactions between these products and other mediators. Continuing studies on the nature of the lipoxygenase involved in leukotriene synthesis will be discussed as will the nature of the ...
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Cytokine mediators of renal inflammation
Current Opinion in Nephrology and Hypertension, 1994This review focuses on the role of two cytokines, platelet-derived growth factor and transforming growth factor-beta, in glomerular injury. The most recent in vitro and in vivo evidence for the role of platelet-derived growth factor and transforming growth factor-beta in glomerular hypercellularity and matrix expansion is summarized.
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