Results 31 to 40 of about 4,346,916 (366)
Cancers, 2018 Inflammation plays a role in the initiation and development of many types of cancers, including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a type of EOC.
S. Savant +2 more
semanticscholar +1 more source
The blood–brain barrier in systemic infection and inflammation
Cellular & Molecular Immunology, 2021 The vascular blood–brain barrier is a highly regulated interface between the blood and brain. Its primary function is to protect central neurons while signaling the presence of systemic inflammation and infection to the brain to enable a protective ...
I. Galea
semanticscholar +1 more source
New roles for Fc receptors in neurodegeneration-the impact on immunotherapy for Alzheimer's disease [PDF]
, 2014 There are an estimated 18 million Alzheimer's disease (AD) sufferers worldwide and with no disease modifying treatment currently available, development of new therapies represents an enormous unmet clinical need.
Fuller, James P. +2 more
core +3 more sources
Science Signaling, 2018 Signaling by the receptor MerTK in macrophages promotes ERK activation and the resolution of inflammation. Promoting resolution The active and coordinated process of inflammation resolution is critical for tissue homeostasis, and defective resolution is ...
Bishuang Cai +5 more
semanticscholar +1 more source
DNA damage mediates changes in neuronal sensitivity induced by the inflammatory mediators, MCP-1 and LPS, and can be reversed by enhancing the DNA repair function of APE1 [PDF]
, 2017 Although inflammation-induced peripheral sensitization oftentimes resolves as an injury heals, this sensitization can be pathologically maintained and contribute to chronic inflammatory pain.
Fehrenbacher, Jill C. +3 more
core +1 more source
Cardiovascular Diabetology, 2017 Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans. Several risk factors promote AF, among which diabetes mellitus has emerged as one of the most important. The growing recognition that obesity, diabetes and AF are closely
B. Karam +4 more
semanticscholar +1 more source
Glial-Mediated Inflammation Underlying Parkinsonism [PDF]
Scientifica, 2013 The interest in studying neuroimmune interactions is increasing in the scientific community, and for many researchers, immunity is becoming a crucial factor in the understanding of the physiology of the normal brain as well as the biology underlying neurodegenerative diseases. Mounting data over the last two decades point toward immune and inflammatory
openaire +6 more sources
Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]
, 2017 The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz +14 more
core +1 more source
Inflammation during the life cycle of the atherosclerotic plaque.
Cardiovascular Research, 2021 Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed, inflammatory mediators likely link many traditional and emerging risk factors with atherogenesis.
P. Libby
semanticscholar +1 more source
CD44 Suppresses TLR-Mediated Inflammation [PDF]
The Journal of Immunology, 2008 Abstract The cell adhesion molecule CD44, which is the major hyaluronan receptor, has been implicated in the binding, endocytosis, and metabolism of hyaluronan. Previous studies have revealed that CD44 plays crucial roles in a variety of inflammatory diseases.
Hidetada, Kawana +6 more
openaire +2 more sources