Results 51 to 60 of about 1,237,469 (299)

Inflammatory mediators, infection, sepsis, and multiorgan failure after severe trauma [PDF]

, 1992
The relation of (multiple) organ failure (OF) to the release of inflammatory mediators and the incidence of infection and sepsis was studied prospectively in 100 patients with multiple trauma (injury severity score=37).
Waydhas, Christian, Trupka, Arnold, Nast-Kolb, Dieter, Schweiberer, Leonhard, Jochum, Marianne, Fritz, Hans, Lenk, Susann, Duswald, Karl-Heimo   +7 more
core   +1 more source

Mediadores químicos e resposta celular na colite induzida pelo DSS: papel dos mediadores lipídicos derivados do omega-3 na resolução da colite experimental [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaAs doenças inflamatórias intestinais (IBD) representam um grupo de disfunções do trato gastrointestinal, que acometem ...
Bento, Allisson Freire
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Novel Method to Process Cystic Fibrosis Sputum for Determination of Oxidative State [PDF]

, 2010
Background: Induced sputum is the most commonly used method to analyze airway inflammation in cystic fibrosis (CF) patients ex vivo. Due to the complex matrix of the sample material, precise and reliable analysis of sputum constituents depends critically
Jonas, F., Hector, A., Kappler, M., Feilcke, M., Griese, M., Hartl, D.   +5 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Resolution of inflammation: Therapeutic potential of pro-resolving lipids in Type 2 diabetes mellitus and associated renal complications

Frontiers in Immunology, 2012
The role of inflammation in the pathogenesis of type 2 diabetes mellitus (T2DM) and its associated complications is increasingly recognized. The resolution of inflammation is actively regulated by endogenously produced lipid mediators such as lipoxins ...
Emma eBorgeson, Catherine eGodson
doaj   +1 more source

Gaseous mediators in resolution of inflammation

Seminars in Immunology, 2015
There are numerous gaseous substances that can act as signaling molecules, but the best characterized of these are nitric oxide, hydrogen sulfide and carbon monoxide. Each has been shown to play important roles in many physiological and pathophysiological processes.
Wallace, John L, IANARO, ANGELA, Flannigan, Kyle L., CIRINO, GIUSEPPE   +3 more
openaire   +4 more sources

Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation [PDF]

, 2011
Background Cytochrome-P450 (CYP450) epoxygenases metabolise arachidonic acid (AA) into four different biologically active epoxyeicosatrienoic acid (EET) regioisomers.
Geisslinger, Gerd, Gerd Geisslinger, Brandes, Ralf P., Brandes, Ralf, Michael J Fischer, Fleming, Ingrid, Scholich, Klaus, Woolf Clifford J, Ralf P Brandes, Clifford J Woolf, Fleming Ingrid, Reeh, Peter Werner, Brenneis Christian, Fischer, Michael, Coste Ovidiu, Coste, Ovidiu, Brandes Ralf P, Kai Altenrath, Reeh Peter W, Christian Brenneis, Scholich Klaus, Sisignano, Marco, Reeh, Peter W., Altenrath Kai, Ingrid Fleming, Peter W Reeh, Woolf, Clifford J., Angioni Carlo, Geisslinger Gerd, Angioni, Carlo Federico, Klaus Scholich, Brenneis, Christian, Ovidiu Coste, Carlo Angioni, Sisignano Marco, Marco Sisignano, Fischer, Michael J., Fischer Michael J, Altenrath, Kai, Angioni, Carlo   +39 more
core   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source