Results 61 to 70 of about 1,237,469 (299)
Background: Periodontitis (PD) and rheumatoid arthritis (RA) are chronic inflammatory conditions, characterized by dysregulated immune response and excessive production of inflammatory mediators. The oral disease PD is triggered by periodontal pathogens,
Tsilingaridis, Georgios, +12 more
core +1 more source
Inflammation in the disease: mechanism and therapies 2014
, 2020 sem ...
Seelaender, M. +4 more
core +1 more source
Influence of natural substances on mediators of intestinal inflammation "in vitro" [PDF]
, 2005 Natural plant extracts and their isolated phenolic substances have been shown to exhibit several functions including the anti-inflammatory activity in various tissues.
Porath, Debora
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Non-inflammatory Physiology of “Inflammatory” Mediators – Unalamation, a New Paradigm
Frontiers in Immunology, 2020 Many small molecules (mostly lipids derived from polyunsaturated fatty acids) and proteins (e. g., cytokines and chemokines) are labeled as inflammatory mediators for their role in eliciting physiological responses to injury.
Krishna Rao Maddipati
doaj +1 more source
Expression analysis of mediators of inflammation.
, 2016 Expression analysis of mediators of inflammation.
Karl F. Hilgers (299648) +8 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Sequential release of cytokines, lipid mediators and nitric oxide in experimental colitis
Mediators of Inflammation, 1995 The object of this study was to establish whether different pro- and anti-inflammatory mediators were formed in colonic tissue from experimental colitis depending on the course of the disease.
A. P. M. van Dijk +3 more
doaj +1 more source
Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins
Mediators of Inflammation, 2020 Acute inflammation has been described as a reactive dynamic process, promoted by the secretion of proinflammatory mediators, including lipid molecules like leukotrienes and prostaglandins, and counterbalanced by proresolving mediators including omega-3 ...
Sajad Chamani +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source