Results 61 to 70 of about 362,551 (290)

IL-6 at the center of cytokine storm: Circulating inflammation mediators as biomarkers in hospitalized COVID-19 patients. [PDF]

J Clin Lab Anal, 2023
Elbadawy HM, Khattab A, El-Agamy DS, Eltahir HM, Alhaddad A, Aljohani FD, Almuzaini TM, Abouzied MM, Aldhafiri A.   +8 more
europepmc   +1 more source

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

FEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran, Gloriana Campos, Natalya M. Wells, Khanhlinh Lambuu, Isabelle Draper, Christina A. Pacak, Peter B. Kang   +6 more
wiley   +1 more source

The systemic-level repercussions of cancer-associated inflammation mediators produced in the tumor microenvironment. [PDF]

Front Endocrinol (Lausanne), 2022
Aguilar-Cazares D, Chavez-Dominguez R, Marroquin-Muciño M, Perez-Medina M, Benito-Lopez JJ, Camarena A, Rumbo-Nava U, Lopez-Gonzalez JS.   +7 more
europepmc   +1 more source

COMPLEMENT AS A MEDIATOR OF INFLAMMATION [PDF]

, 1963
Oscar D. Ratnoff, Irwin H. Lepow
openalex   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

In Vitro Induction of Eryptosis by Uremic Toxins and Inflammation Mediators in Healthy Red Blood Cells. [PDF]

J Clin Med, 2022
Virzì GM, Mattiotti M, Clementi A, Milan Manani S, Battaglia GG, Ronco C, Zanella M.   +6 more
europepmc   +1 more source

MEDIATORS OF INFLAMMATION IN LEUKOCYTE LYSOSOMES [PDF]

, 1965
Aaron Janoff, Sonja Schaefer, Joan Scherer, Michael A. Bean   +3 more
openalex   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Unraveling the Complex Relationship Triad between Lipids, Obesity, and Inflammation

Mediators of Inflammation, 2014
Obesity today stands at the intersection between inflammation and metabolic disorders causing an aberration of immune activity, and resulting in increased risk for diabetes, atherosclerosis, fatty liver, and pulmonary inflammation to name a few ...
Shahida A. Khan, Ashraf Ali, Sarah A. Khan, Solafa A. Zahran, Ghazi Damanhouri, Esam Azhar, Ishtiaq Qadri   +6 more
doaj   +1 more source

Accelerated brain aging with opioid misuse and HIV: New insights on the role of glially derived pro-inflammation mediators and neuronal chloride homeostasis. [PDF]

Curr Opin Neurobiol, 2023
Hauser KF, Ohene-Nyako M, Knapp PE.
europepmc   +1 more source