Results 71 to 80 of about 4,616,582 (290)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Obese patients with a binge eating disorder have an unfavorable metabolic and inflammatory profile [PDF]

open access: yes, 2015
To evaluate whether obese patients with a binge eating disorder (BED) have an altered metabolic and inflammatory profile related to their eating behaviors compared with non-BED obese.A total of 115 White obese patients consecutively recruited underwent ...
Aloi, M   +8 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Role of Enteral Immunonutrition in Patients with Gastric Carcinoma Undergoing Major Surgery

open access: yesAsian Journal of Surgery, 2005
To evaluate the influence of postoperative immunonutrition on immune and nutritional parameters in patients with gastric carcinoma. Methods: From September 2002 to August 2003, 40 patients with gastric carcinoma who had undergone major surgery were ...
Da Wei Chen   +4 more
doaj   +1 more source

Management of inflammatory dentigerous cysts in children : report of two cases [PDF]

open access: yes, 2010
Inflammatory dentigerous cysts are usually associated with a carious or non-vital primary tooth. Consequently they are found in children with a mixed dentition.
Azzopardi, Alexander, Scerri, Erica
core  

Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection [PDF]

open access: yes, 2015
Bioactive matrix fragments (matrikines) have been identified in a myriad of disorders, but their impact on the evolution of airway inflammation has not been demonstrated.
Snelgrove, RJ
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Role of Interleukin-33 in Immunity and Periodontal Inflammation-A Literature Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
The Interleukin-33 (IL-33) is a member of IL-1 family discovered in the year of 2005. The Interleukin-1 (IL-1) family of cytokines is commonly encountered in chronic inflammatory diseases such as rheumatoid arthritis and periodontitis.
Sasi Kumar Karuppanan   +2 more
doaj   +1 more source

Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation [PDF]

open access: yes, 2020
Receptor interacting protein kinase 1 (RIPK1) regulates cell death and inflammatory responses downstream of TNFR1 and other receptors, and has been implicated in the pathogenesis of inflammatory and degenerative diseases.
Bertrand, Mathieu   +11 more
core   +1 more source

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