Results 131 to 140 of about 371,945 (298)

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Adaptable Covalent Organic Framework‐Hydrogel Microneedles for Glucose‐Responsive Isoliquiritigenin Delivery in Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou, Zongjie Hu, Xiuwen Li, Huaman Geng, Yang Liu, Yajie Wang, Yunshu Yang, Guangdong Zhou, Yujie Hua, Di Wang   +9 more
wiley   +1 more source

Plasma Epstein-Barr Virus DNA load for diagnostic and prognostic assessment in intestinal Epstein-Barr Virus infection

Frontiers in Cellular and Infection Microbiology
BackgroundThe prospective application of plasma Epstein-Barr virus (EBV) DNA load as a noninvasive measure of intestinal EBV infection remains unexplored.
Chunxiang Ma, Chunxiang Ma, Chunxiang Ma, Mingshan Jiang, Mingshan Jiang, Mingshan Jiang, Jiaxin Li, Jiaxin Li, Jiaxin Li, Zhen Zeng, Zhen Zeng, Zhen Zeng, Yushan Wu, Yushan Wu, Yushan Wu, Rui Cheng, Rui Cheng, Rui Cheng, Hao Lin, Hao Lin, Hao Lin, Jiangmei Pang, Jiangmei Pang, Jiangmei Pang, Fang Yin, Fang Yin, Fang Yin, Yongbin Jia, Yongbin Jia, Yongbin Jia, Lili Li, Lili Li, Lili Li, Hu Zhang, Hu Zhang, Hu Zhang   +35 more
doaj   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Impact of a nurse‐led counselling service on quality of life in patients with inflammatory bowel disease

, 2002
Impact of a nurse-led counselling service upon quality of life in patients with inflammatory bowel diseaseAim. Health related quality of life is impaired in patients suffering from inflammatory bowel disease.
Luman, Widjaja, Kelvin R. Palmer, Graeme D. Smith, Nigel Hurst, Roger, Derek, McRorie, Euan, Smith, Graeme D., Euan McRorie, Derek Roger, Hurst, Nigel, Widjaja Luman, Roger Watson, Watson, Roger, Palmer, Kelvin R.   +13 more
core   +1 more source

Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues

Advanced Materials Interfaces, EarlyView.
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike, Dhananjay V. Deshmukh, Mark W. Tibbitt, Céline Labouesse   +3 more
wiley   +1 more source

Two Worlds, One Life: Narrative Spaces of Identity Between Health and Illness

, 2009
This paper reports a component of a larger study about how adolescents adapt to chronic illness. The condition in question was Inflammatory Bowel Disease (IBD), a medical term for two conditions, ulcerative colitis and Crohn’s disease. Ulcerations appear
Gross, Harriet, Sargeant, Sally J E, Sargeant, Sally, Middleton, David   +3 more
core  

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Toll-like receptor 7 protects against intestinal inflammation and restricts the development of colonic tissue-resident memory CD8+ T cells

Frontiers in Immunology
IntroductionThe maintenance of intestinal homeostasis depends on a complex interaction between the immune system, intestinal epithelial barrier, and microbiota.
Hussein Hamade, Masato Tsuda, Naoki Oshima, Dalton T. Stamps, Michelle H. Wong, Jasmine T. Stamps, Lisa S. Thomas, Brenda C. Salumbides, Caroline Jin, Jordan S. Nunnelee, Deepti Dhall, Stephan R. Targan, Kathrin S. Michelsen, Kathrin S. Michelsen   +13 more
doaj   +1 more source