Unraveling the Link between Periodontitis and Inflammatory Bowel Disease: Challenges and Outlook [PDF]
arXiv, 2023 Periodontitis and Inflammatory Bowel Disease (IBD) are chronic inflammatory conditions, characterized by microbial dysbiosis and hyper-immunoinflammatory responses. Growing evidence suggest an interconnection between periodontitis and IBD, implying a shift from the traditional concept of independent diseases to a complex, reciprocal cycle.
arxiv
Network analysis of a complex disease: the gut microbiota in the inflammatory bowel disease case [PDF]
arXiv, 2022 Inflammatory bowel diseases (IBD) are complex diseases in which the gut microbiota is attacked by the immune system of genetically predisposed subjects when they are exposed to yet unclear environmental factors. The complexity of this class of diseases makes them suitable to be represented and studied with network science.
arxiv
Living with Inflammatory Bowel Disease: A Crohn’s and Colitis Canada Survey
Canadian Journal of Gastroenterology and Hepatology, 2015 BACKGROUND: Despite improvements in therapies for inflammatory bowel diseases (IBDs), patient quality of life continues to be significantly impacted.
Helen M Becker +9 more
doaj +1 more source
Interpretable histopathology-based prediction of disease relevant features in Inflammatory Bowel Disease biopsies using weakly-supervised deep learning [PDF]
arXiv, 2023 Crohn's Disease (CD) and Ulcerative Colitis (UC) are the two main Inflammatory Bowel Disease (IBD) types. We developed deep learning models to identify histological disease features for both CD and UC using only endoscopic labels. We explored fine-tuning and end-to-end training of two state-of-the-art self-supervised models for predicting three ...
arxiv
Intestinal Research, 2017 Background/Aims: Recent genome-wide analyses have provided strong evidence concerning adverse events caused by thiopurine drugs such as azathioprine (AZA) and 6-mercaptopurine.
Toshiyuki Sato +13 more
doaj +1 more source
Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease
Scientific Reports, 2021 CARMIL2 is required for CD28-mediated co-stimulation of NF-κB signaling in T cells and its deficiency has been associated with primary immunodeficiency and, recently, very early onset inflammatory bowel disease (IBD).
Luca Bosa +21 more
doaj +1 more source
Living with Inflammatory Bowel Disease: A review of qualitative research studies [PDF]
, 2018 © 2018 Elsevier Ltd Background: Inflammatory Bowel Disease is a chronic, untreatable condition represented by two illnesses, Crohn's and Ulcerative Colitis.
Aveyard, H, Fourie, S, Jackson, D
core +2 more sources
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Extracts of Feijoa Inhibit Toll-Like Receptor 2 Signaling and Activate Autophagy Implicating a Role in Dietary Control of IBD [PDF]
, 2015 Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory disease affecting the gut with limited treatment success for its sufferers.
A Asea +39 more
core +4 more sources
Changing patterns in the epidemiology and outcomes of inflammatory bowel disease in the United Kingdom: 2000-2018 [PDF]
, 2020 Background: Data regarding incidence, prevalence and long-term outcomes of inflammatory bowel diseases in the UK are limited or outdated.Aims: To investigate incidence and prevalence of Crohn's disease and ulcerative colitis and risk of colorectal cancer
Aniwan +50 more
core +1 more source