Clinical features of very early-onset inflammatory bowel disease in Japan: a retrospective single-center study [PDF]
Intestinal Research, 2022 Background/Aims Very early-onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed in patients younger than 6 years, is a challenge for pediatric gastroenterologists.
Masaaki Usami +8 more
doaj +1 more source
Gut microbiome structure and metabolic activity in inflammatory bowel disease
Nature Microbiology, 2018 The inflammatory bowel diseases (IBDs), which include Crohn’s disease (CD) and ulcerative colitis (UC), are multifactorial chronic conditions of the gastrointestinal tract.
E. Franzosa +26 more
semanticscholar +1 more source
Quantitative Risk-Benefit Analysis of Probiotic Use for Irritable Bowel Syndrome and Inflammatory Bowel Disease [PDF]
, 2016 Probiotics have seen widespread use for a variety of gastrointestinal problems, especially in two common disorders: irritable bowel syndrome and inflammatory bowel disease. Since a wide variety of probiotic preparations has been used, and despite a large
Bennett, William E., Jr.
core +1 more source
Scientific Reports, 2021 Intestinal dysbiosis is key in the onset and development of Crohn’s disease (CD). We evaluated the microbiota changes in CD patients before and after a six-month anti-TNF treatment, comparing these changes with the microbiota of healthy subjects.
Laura Sanchis-Artero +11 more
doaj +1 more source
Faecal leukocyte esterase activity is an alternative biomarker in inflammatory bowel disease [PDF]
, 2015 Background: Leukocyte cytosolic proteins (e.g., calprotectin) are emerging biomarkers for inflammatory bowel disease. Leukocyte aryl esterase activity has been commonly used for sensitive detection of leukocytes in human body fluids such as urine.
De Vos, Martine +5 more
core +2 more sources
Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment
Genome Biology, 2012 The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis result from alterations in intestinal microbes and the immune system. However, the precise dysfunctions of microbial metabolism in the gastrointestinal microbiome during IBD ...
X. Morgan +14 more
semanticscholar +1 more source
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2005 The discovery of a series of genetic and serological markers associated with disease susceptibility and phenotype in inflammatory bowel disease has led to the prospect of an integrated classification system involving clinical, serological and genetic ...
M. Silverberg +21 more
semanticscholar +1 more source
Management of Anal Fistula with Crohn's Disease
Journal of the Anus, Rectum and ColonCrohn's disease (CD) causes gastrointestinal symptoms (i.e., diarrhea and abdominal pain), systemic symptoms (i.e., fatigue, anemia, weight loss, and fever), and perianal fistulas that produce anal pain. Because of the frequent occurrence of diarrhea and
Shota Takano +5 more
doaj +1 more source
Frontiers in Immunology, 2022 Crohn’s disease (CD) is a chronic intestinal disorder characterized by refractory gastrointestinal ulcerations. Intestinal tuberculosis (ITB) is one common intestinal disease in east Asia.
Mingshan Jiang +29 more
doaj +1 more source
Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]
, 2006 The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon +4 more
core +1 more source