Results 191 to 200 of about 1,070,166 (331)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Roles of Deubiquitinases OTUD3 and OTUD5 in Inflammatory Bowel Diseases. [PDF]

Int J Mol Sci
Watanabe T, Kudo M.
europepmc   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Association Between Maternal IBD-Related Antibodies and Early Life Gut Inflammatory Status and Microbiota Composition: Insights from Cord Blood

Journal of Inflammation Research
Taegyu Kim,1 Paola Nicoletti,1 Maria Manuela Estevinho,2,3 Leonid Tarassishin,1 Mellissa Picker,1 Anketse Debebe,1 Isabella Nguyen,1 Rhiannon Dutra-Clarke,4 Courtney Young,4 Joanne Stone,5 Ariella Bar-Gil Shitrit,6 Manasi Agrawal,7 Jean-Frederic Colombel,
Kim T, Nicoletti P, Estevinho MM, Tarassishin L, Picker M, Debebe A, Nguyen I, Dutra-Clarke R, Young C, Stone J, Bar-Gil Shitrit A, Agrawal M, Colombel JF, Torres J, Ng SC, Zhang L, McGovern DPB, Peter I   +17 more
doaj  

Extranodal NK/T-cell lymphoma: An unexpected cause of postoperative fever in a young male

Asian Journal of Surgery, 2021
Wenhao Chen, Junjie Zhou, Congqing Jiang, Qun Qian, Zhao Ding   +4 more
doaj   +1 more source

Chemerin as a biomarker of inflammatory bowel diseases: a meta-analysis. [PDF]

BMC Gastroenterol
Tian Z, Xiang Q, Long M, Liao J, Wang F, Li X.   +5 more
europepmc   +1 more source

Thromboembolic complications in children with inflammatory bowel disease

E. I. Alieva, O. V. Shcherbakova, I. V. Zyabkin   +2 more
openalex   +2 more sources

The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease

, 2011
Sarah Ingersoll, Saravanan Ayyadurai, Moiz A. Charania, Hamed Laroui, Yutao Yan, Didier Merlin   +5 more
openalex   +2 more sources

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Interoception in Female Adolescents with Inflammatory Bowel Diseases <i>Versus</i> Restrictive Eating Disorders. [PDF]

Nutrients
Riva A, Arienti G, Panarella C, Brasola E, Di Guardo S, Zuin G, Spini L, Sansotta N, Cavanna AE, Nacinovich R.   +9 more
europepmc   +1 more source