Results 221 to 230 of about 398,299 (327)

Assessing nutritional state in inflammatory bowel disease. [PDF]

, 1986
R V Heatley
openalex   +1 more source

Asia Pacific association of gastroenterology consensus statements on histopathological evaluation of inflammatory bowel diseases. [PDF]

Therap Adv Gastroenterol
Leong RW, Chaemsupaphan T, Lin H, Chian Lim W, Ooi CJ, Chetwood JD, Mao R, Wu HY, Wei SC, Makharia G, Ahuja V, Banerjee R, Atreya R, Limsrivilai J, Aniwan S, Pisespongsa P, Hilmi I, Raja Ali RA, Leung WK, Ng SC, Ye BD, Kobayashi T, Matsuoka K, Chau C, Sanpavat A, Shun CT, Puspanathan P, Gearry RB, Danese S, Ma C, Pudipeddi A, Paramsothy S.   +31 more
europepmc   +1 more source

Reprogramming of Fatty Acid Metabolism via PPARα‐Orchestrated FADS2 in Keratinocytes Modulates Skin Inflammation in Psoriasis

Advanced Science, EarlyView.
This study identifies fatty acid desaturase 2 (FADS2) as a key regulator linking polyunsaturated fatty acid (PUFA) metabolism to psoriatic inflammation. FADS2 deficiency impairs docosahexaenoic acid (DHA) biosynthesis, enhances NF‐κB signaling, and promotes neutrophil‐driven skin inflammation. PPARα transcriptionally activates FADS2, and its activation
Jiangluyi Cai, Xue Zhou, Yu Zhuang, Lian Cui, Rui Ma, Youdong Chen, Nan Yang, Qianyu Chen, Yuanyuan Wang, Peiyao Zhu, Lingling Yao, Qian Yu, Xiaomin She, Xuyang Zhou, Yuemeng Huang, Zengyang Yu, Xilin Zhang, Jiajing Lu, Yuling Shi, Chunyuan Guo   +19 more
wiley   +1 more source

RESULTS OF SURGICAL TREATMENT OF IDIOPATHIC INFLAMMATORY BOWEL DISEASE

, 1979
Tetsuichiro Muto, J Kamiya, Satoru Kusama   +2 more
openalex   +2 more sources

Molecular Basis of Chronic Intestinal Wall Fibrosis in Inflammatory Bowel Diseases. [PDF]

Int J Mol Sci
Sputa-Grzegrzolka P, Socha-Banasiak A, Dziegiel P, Kempisty B.   +3 more
europepmc   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

Carrier‐Free Nanocapsule with Dual‐Target Capacity for Synergistically Restoring Inflammatory Microenvironment and Microbiota Dysbiosis in Colitis

Advanced Science, EarlyView.
This manuscript presents a carrier‐free nanomedicine PCNPs@PEG‐Man with dual‐targeting for IBD. It resists harsh intestinal conditions, reduces oxidative stress, enhances drug uptake and retention, modulates inflammation, and reshapes gut microbiota, offering a safe and effective IBD therapy.
Yingjie Chen, Yuhan Gao, Kaiyuan Huo, Zhaofan Jin, Wenchao Wang, Xingjie Zan, Yanlong Liu, Limeng Zhu, Jianfeng Yang   +8 more
wiley   +1 more source

Failure to record variables of growth and development in children with inflammatory bowel disease. [PDF]

, 1989
J R Barton, A Ferguson
openalex   +1 more source

Translocator protein facilitates neutrophil-mediated mucosal inflammation in inflammatory bowel diseases. [PDF]

World J Gastroenterol
He Q, Wu XH, Jiang DL, Lin RT, Xie F, Guan YH, Fei AH.   +6 more
europepmc   +1 more source