Results 241 to 250 of about 437,829 (320)

Three-dimensional multicellular layer structure: an advanced in vitro model for studying inflammatory bowel diseases. [PDF]

Sci Rep
Zaramella A, Dorigo Hochuli AH, Duci M, Marcigaglia M, Moll-Diaz R, Bisaccia P, Kashyap R, Jurga M, Muraca M, Pozzobon M.   +9 more
europepmc   +1 more source

Leucaena leucocephala succinate based polyelectrolyte complexes for colon delivery of synbiotic in management of inflammatory bowel disease [PDF]

Gaganpreet Kaur, Aman Kumar, Samridhi Kurl, Neeraj Mittal, Deepinder Singh Malik, Pallavi Bassi, Tanveer Singh, Azmat Ali Khan, Amer M. Alanazi, Gurpreet Kaur   +9 more
openalex   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Memory in Misfire: The Gut Microbiome-Trained Immunity Circuit in Inflammatory Bowel Diseases. [PDF]

Int J Mol Sci
Yang B, Wu J, Hou X, Bai T, Liu S.
europepmc   +1 more source

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source

Macrophage Metabolic Reprogramming in Inflammatory Bowel Diseases: From Pathogenesis to Therapy. [PDF]

J Inflamm Res
Zhang YF, Shi TT, Lin YL, Zhu YT, Lin S, Fang TY.   +5 more
europepmc   +1 more source

Assessing Highly Processed Food Consumption in Patients with Inflammatory Bowel Disease: Application of the German Screening Questionnaire (sQ-HPF) [PDF]

Lea Pueschel, Sonja Nothacker, Lisa Kühn, Heiner Wedemeyer, Henrike Lenzen, Miriam Wiestler   +5 more
openalex   +1 more source

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

Advanced Science, EarlyView.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang   +16 more
wiley   +1 more source

Probiotics in inflammatory bowel diseases: emphasis on mechanisms and clinical application. [PDF]

Front Med (Lausanne)
Zhang J, Zhang X, Cheng X, Wang S, Lv Y, Zheng X, Wu G.   +6 more
europepmc   +1 more source

Cocaine- and amphetamine-regulated transcript immunoreactive nerve fibres in the mucosal layer of the canine gastrointestinal tract under physiological conditions and in inflammatory bowel disease

, 2015
Andrzej Rychlik, Sławomir Gonkowski, Marcin Nowicki, Jarosław Całka   +3 more
openalex   +1 more source