Results 241 to 250 of about 387,427 (329)

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

open access: yesAdvanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu   +6 more
wiley   +1 more source

The Role of Vitamin D in Inflammatory Bowel Diseases: From Deficiency to Targeted Therapeutics and Precise Nutrition Strategies. [PDF]

open access: yesNutrients
Dell'Anna G   +17 more
europepmc   +1 more source

Thrombosis as a Complication of Inflammatory Bowel Disease in Children

open access: bronze, 1985
Khazal Paradis   +2 more
openalex   +1 more source

ACSS2‐Mediated Histone H4 Lysine 12 Crotonylation (H4K12cr) Alleviates Colitis via Enhancing Transcription of CLDN7

open access: yesAdvanced Science, EarlyView.
Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan   +14 more
wiley   +1 more source

Hepatotoxic Effect of Bile Acids in Inflammatory Bowel Disease

open access: bronze, 1980
M. J. Dew   +3 more
openalex   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

open access: yesAdvanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian   +9 more
wiley   +1 more source

Proteomic Profiling of Extracellular Vesicles in Inflammatory Bowel Diseases. [PDF]

open access: yesInt J Mol Sci
Baldán-Martín M   +14 more
europepmc   +1 more source

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