Results 21 to 30 of about 301,386 (199)

Preventative therapies for healthy women at high risk of breast cancer [PDF]

open access: yes, 2014
Ivana Sestak Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, UKAbstract: Tamoxifen has been shown to reduce the risk of developing estrogen receptor (ER)-positive ...
Sestak I, Sestak, I
core   +1 more source

Ablation of Stromal Cells with a Targeted Proapoptotic Peptide Suppresses Cancer Chemotherapy Resistance and Metastasis

open access: yesMolecular Therapy: Oncolytics, 2020
Adipose stromal cells (ASCs) recruited by tumors contribute to the population of cancer-associated fibroblasts. ASCs have been reported to induce tumor growth and chemotherapy resistance. The effect of ASCs on metastasis has not been explored.
Fei Su   +6 more
doaj   +1 more source

Update on inflammatory breast cancer [PDF]

open access: yesBreast Cancer Research, 2005
Inflammatory breast cancer (IBC) is both the least frequent and the most severe form of epithelial breast cancer. The diagnosis is based on clinical inflammatory signs and is reinforced by pathological findings. Significant progress has been made in the management of IBC in the past 20 years.
Lerebours, Florence   +2 more
openaire   +2 more sources

p53 mutation, deprivation and poor prognosis in primary breast cancer [PDF]

open access: yes, 2010
Background: The deprivation gap for breast cancer survival remains unexplained by stage at presentation, treatment, or co-morbidities. We hypothesised that p53 mutation might contribute to the impaired outcome observed in patients from deprived ...
P R Quinlan   +30 more
core   +1 more source

Ultrastructural Analysis of Inflammatory Breast Cancer Cell Clusters in an Ex Vivo Environment Mechanically Mimicking the Lymph Vascular System

open access: yesBreast Cancer: Basic and Clinical Research, 2021
Background: Inflammatory breast cancer (IBC) is a rare form of breast cancer with a poor prognosis. IBC is characterized by florid lymphovascular tumor emboli in the skin and the parenchyma of the breast.
Yuka Fujii   +2 more
doaj   +1 more source

Risk determination and prevention of breast cancer [PDF]

open access: yes, 2014
Breast cancer is an increasing public health problem. Substantial advances have been made in the treatment of breast cancer, but the introduction of methods to predict women at elevated risk and prevent the disease has been less successful.
Howell, Anthony; id_orcid   +55 more
core   +1 more source

miRNome of inflammatory breast cancer [PDF]

open access: yesBMC Research Notes, 2014
Inflammatory breast cancer (IBC) is an extremely malignant form of breast cancer which can be easily misdiagnosed. Conclusive prognostic IBC molecular biomarkers which are also providing the perspectives for targeted therapy are lacking so far. The aim of this study was to reveal the IBC-specific miRNA expression profile and to evaluate its association
Maltseva, Diana V   +11 more
openaire   +2 more sources

A central review of histopathology reports after breast cancer neoadjuvant chemotherapy in the neo-tango trial [PDF]

open access: yes, 2013
Background: Neo-tAnGo, a National Cancer Research Network (NCRN) multicentre randomised neoadjuvant chemotherapy trial in early breast cancer, enroled 831 patients in the United Kingdom.
K Walland   +25 more
core   +1 more source

Inflammatory cytokines and two subtypes of breast cancer: A two-sample mendelian randomization study.

open access: yesPLoS ONE, 2023
BackgroundBreast cancer is a common cancer type that leads to cancer-related deaths among women. HER2-positive breast cancer, in particular, is associated with poor prognosis due to its high aggressiveness, increased risk of recurrence, and metastasis ...
Heran Zhou   +5 more
doaj   +1 more source

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer [PDF]

open access: yes, 2013
IntroductionBreast cancer remains a significant scientific, clinical and societal challenge. This gap analysis has reviewed and critically assessed enduring issues and new challenges emerging from recent research, and proposes strategies for translating ...
Gee, Julia M. W.   +592 more
core   +1 more source

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