Results 21 to 30 of about 291,938 (249)

Ablation of Stromal Cells with a Targeted Proapoptotic Peptide Suppresses Cancer Chemotherapy Resistance and Metastasis

open access: yesMolecular Therapy: Oncolytics, 2020
Adipose stromal cells (ASCs) recruited by tumors contribute to the population of cancer-associated fibroblasts. ASCs have been reported to induce tumor growth and chemotherapy resistance. The effect of ASCs on metastasis has not been explored.
Fei Su   +6 more
doaj   +1 more source

Update on inflammatory breast cancer [PDF]

open access: yesBreast Cancer Research, 2005
Inflammatory breast cancer (IBC) is both the least frequent and the most severe form of epithelial breast cancer. The diagnosis is based on clinical inflammatory signs and is reinforced by pathological findings. Significant progress has been made in the management of IBC in the past 20 years.
Lerebours, Florence   +2 more
openaire   +2 more sources

Ultrastructural Analysis of Inflammatory Breast Cancer Cell Clusters in an Ex Vivo Environment Mechanically Mimicking the Lymph Vascular System

open access: yesBreast Cancer: Basic and Clinical Research, 2021
Background: Inflammatory breast cancer (IBC) is a rare form of breast cancer with a poor prognosis. IBC is characterized by florid lymphovascular tumor emboli in the skin and the parenchyma of the breast.
Yuka Fujii   +2 more
doaj   +1 more source

miRNome of inflammatory breast cancer [PDF]

open access: yesBMC Research Notes, 2014
Inflammatory breast cancer (IBC) is an extremely malignant form of breast cancer which can be easily misdiagnosed. Conclusive prognostic IBC molecular biomarkers which are also providing the perspectives for targeted therapy are lacking so far. The aim of this study was to reveal the IBC-specific miRNA expression profile and to evaluate its association
Maltseva, Diana V   +11 more
openaire   +2 more sources

Inflammatory cytokines and two subtypes of breast cancer: A two-sample mendelian randomization study.

open access: yesPLoS ONE, 2023
BackgroundBreast cancer is a common cancer type that leads to cancer-related deaths among women. HER2-positive breast cancer, in particular, is associated with poor prognosis due to its high aggressiveness, increased risk of recurrence, and metastasis ...
Heran Zhou   +5 more
doaj   +1 more source

Lymphoma of the breast: A mimic of inflammatory breast cancer [PDF]

open access: yesWorld Journal of Surgical Oncology, 2011
Unusual presentation of breast lymphoma with signs and symptoms suggestive of inflammatory breast cancer.Lymphoma of the breast is uncommon whether it is primary or secondary. Most breast lymphomas are of B cell origin. The most frequent mode of presentation is a painless breast mass.
Pallapothu Ratnakishore, Anne Nirupama
openaire   +3 more sources

Inflammatory conversion of quiescent osteoblasts by metastatic breast cancer cells through pERK1/2 aggravates cancer-induced bone destruction

open access: yesBone Research, 2021
Disruption of bone homeostasis caused by metastatic osteolytic breast cancer cells increases inflammatory osteolysis and decreases bone formation, thereby predisposing patients to pathological fracture and cancer growth. Alteration of osteoblast function
Jungho Back   +18 more
doaj   +1 more source

Trastuzumab in inflammatory breast cancer

open access: yesAnnals of Oncology, 2008
Inflammatory breast cancer (IBC) is associated with poor survival, specifically hormone receptor-negative subtype [1]. The dose-dense chemotherapy scheduling may be important in IBC as IBC is hyperproliferative, more often epidermal growth factor receptor-2 positive (HER2+), and hormone receptor negative [2, 3]. Separately, trastuzumab modulates DNA–
R S, Mehta, T, Schubbert, K, Kong
openaire   +2 more sources

Clinical trial-identified inflammatory biomarkers in breast and pancreatic cancers

open access: yesFrontiers in Endocrinology, 2023
Breast cancer and pancreatic cancer are two common cancer types characterized by high prevalence and high mortality rates, respectively. However, breast cancer has been more well-studied than pancreatic cancer.
Jing Peng   +4 more
doaj   +1 more source

The role of three-dimensional in vitro models in modelling the inflammatory microenvironment associated with obesity in breast cancer

open access: yesBreast Cancer Research, 2023
Obesity is an established risk factor for breast cancer in postmenopausal women. However, the underlying biological mechanisms of how obesity contributes to breast cancer remains unclear.
Rhianna Rachael Romany Blyth   +2 more
doaj   +1 more source

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