Results 101 to 110 of about 1,012,717 (304)
, 2020 Inflammation and cancerogenesis are strongly interconnected processes, not only because inflammation promotes DNA instability, but also because both processes are driven by pathways such as NF-kB, STAT3, mTOR and MAPKs.
D'Orazi, Gabriella +2 more
core +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Temporal patterns of inflammatory gene expression in local tissues after banding or burdizzo castration in cattle [PDF]
, 2009 peer-reviewedBackground: Castration of male cattle has been shown to elicit inflammatory reactions and acute inflammation is initiated and sustained by the participation of cytokines.
Gath Vivian +9 more
core +1 more source
Cytokine Therapy in Bladder Cancer: Mechanisms, Efficacy, and Future Prospects
Current Issues in Molecular BiologyCytokine therapy is a rapidly evolving field in bladder cancer research, with treatments designed to enhance immune responses, improve targeting, and promote tumor cell recognition and elimination.
Hayden J. Oyler +6 more
doaj +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
A role for polyunsaturated fatty acids in Th1-mediated disease [PDF]
, 2008 The anti-inflammatory effects of polyunsaturated fatty acids (PUFA) have been well documented, however their exact method of action remains elusive. Dendritic cells (DC) are the most potent antigen presenting cell (APC) and we found that n-3 and n-6 PUFA
Draper, Eve
core
Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis
, 2004 Streptococcus uberis and Serratia marcescens are Gram-positive and Gram-negative bacteria, respectively, that induce clinical mastitis. Once initial host barrier systems have been breached by these pathogens, the innate immune system provides the next ...
Bannerman, Douglas +20 more
core +1 more source