Results 71 to 80 of about 2,144,005 (298)

Cytokine expression by inflammatory neutrophils [PDF]

FEMS Immunology & Medical Microbiology, 1994
Bloodstream neutrophils do not express mRNA for interleukin-1 beta (IL-1 beta), but transcripts for this cytokine are rapidly induced following exposure to recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) in vitro. Levels of IL-1 beta mRNA reach maximal values 1 h after exposure to rGM-CSF and then decline to near basal levels by ...
J A, Quayle, S, Adams, R C, Bucknall, S W, Edwards   +3 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Association of Vitamin B12 with pro-inflammatory cytokines and biochemical markers related to cardiometabolic risk in Saudi subjects [PDF]

, 2016
Background This study aimed to examine the relationship between changes in systemic vitamin B12 concentrations with pro-inflammatory cytokines, anthropometric factors and biochemical markers of cardiometabolic risk in a Saudi population. Methods
Wani, Kaiser, Saravanan, P, Saravanan, Ponnusamy, Saravanan, P., McTernan, P.G, Kaiser Wani, Sabico, Shaun, Wani, K., Wani, K, Alokail, M.S., Tripathi, G, Shakilur Rahman, Philip McTernan, Omar Al-Attas, Al-Daghri, Nasser, Tripathi, G., Yakout, S., Al-Attas, O.S, Nasser Al-Daghri, Majed Alokail, Sabico, S, Gyanendra Tripathi, Tripathi, Gyanendra, Rahman, S., Sabico, S., Rahman, S, Alokail, M.S, Rahman, Shakilur, McTernan, P. G., Yakout, S, Alokail, Majed, Al-Daghri, N.M, Yakout, Sobhy, McTernan, P.G., Shaun Sabico, Al-Attas, O.S., Al-Attas, Omar, Al-Daghri, N.M., Ponnusamy Saravanan, Sobhy Yakout, McTernan, PG, Alokail, MS, Al-Attas, OS, Al-Daghri, NM   +43 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Systemic Inflammatory Response Syndrome Due to Surgery and its Effective Therapeutic Approaches

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: Various lesions trigger an inflammatory response in the host body. These injuries include surgical stress Surgery exerts stress on the body.
Moosa Javdani, Abolfazl Barzegar-Bafrouei   +1 more
doaj  

Inflammatory cytokines activity in temporomandibular joint disorders: a review of literature

Brazilian Journal of Oral Sciences, 2015
Cytokines are important polypeptides mediators of acute and chronic inflammation. These molecules act as a complex immunological network, in which there are pro-inflammatory cytokines, such as interleukin-1 (IL-1), IL-6 and tumor necrosis factor-a (TNF-a)
Maria Isabela Guimarães Campos, Paulo Sérgio Flores Campos, Sergio Roberto Peres Line   +2 more
doaj   +1 more source

短期胰岛素强化治疗对新诊断的2型糖尿病患者炎性细胞因子的影响

Journal of Diabetes, 2022
Background Diabetes mellitus was a chronic low‐grade inflammatory disease and had increased circulating inflammatory cytokines and acute phase proteins.
Junyu He, Peiji Dai, Liyi Liu, Yanqing Yang, Xibo Liu, Yanbing Li, Zhihong Liao   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

CSF-1 as a regulator of macrophage activation and immune responses [PDF]

, 2003
Macrophage activation is a key determinant of susceptibility and pathology in a variety of inflammatory diseases. The extent of macrophage activation is tightly regulated by a number of pro-inflammatory cytokines (e.g.
Sweet, MJ, Sweet, Matthew J, Hume, David A, Hume, DA   +3 more
core  

Cytokines and pulmonary inflammatory and immune diseases [PDF]

, 2011
Cytokines are important soluble signalling molecules that dictate and coordinate inflammatory and immune responses. Further understanding the role of cytokines in the pathobiologic mechanisms of pulmonary inflammatory and immune diseases holds the key to
Gauldie, J., Xing, Zhou, Wang, J., Jordana, M.   +3 more
core   +1 more source