Results 71 to 80 of about 998,241 (312)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Normal inflammatory markers and acute appendicitis: a national multicentre prospective cohort analysis

, 2021
PURPOSE: For the diagnosis of acute appendicitis, the combination of clinical and laboratory variables achieves high diagnostic accuracy. Nevertheless, appendicitis can present with normal laboratory tests of inflammation.
van Dessel, E., de Castro, S. M., Boekestijn, B., de Jonge, J., Akkermans, B., Dettmers, R., van der Peet, D. L., van Rossem, C. C., van den Boom, A. L., Busch, O. R., Dulfer, R. R., van der Elst, M., Allema, J. H., Dohmen, F. Y., Boerma, D., van Duijvendijk, P., van Dalen, T., Dwars, B. J., Groot, J., Bemelman, W. A., Bouwense, S. A., van den Ende, E., Andeweg, C. S., Cense, H. A., Appeldoorn, N., den Bakker, C. M., Boute, M. C., Dawson, I., den Boer, F. C., van Dongen, K. W., van Acker, G. J., Fassaert, L. M., Dhar, N., van den Berg, C., van Heurn, E., Akkersdijk, G. J., Westerduin, E., Algie, G. D., van Brussel, F. A., Mirck, B., Scheijmans, J. C. G., Eerenberg, J. P., van Geloven, A. A. W., Bartels, S. A., Terwisscha van Scheltinga, C., Boermeester, M. A., van Baal, J. G., Bransen, J., Croese, C., Lases, S. S.   +49 more
core   +1 more source

Behavior of inflammatory markers of myocardial injury in cardiac surgery: laboratory correlation with the clinical picture of postpericardiotomy syndrome

Arquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the ...
Ilmar Köhler, Paulo J. Saraiva, Orlando B. Wender, Alcides J. Zago   +3 more
doaj   +1 more source

Association of Inflammatory Markers With Socioeconomic Status [PDF]

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2006
This study examines the association between socioeconomic status (SES) and inflammatory markers in well-functioning older adults and seeks to determine whether any association remains after adjusting for biomedical and behavioral factors typically related to elevated serum levels of inflammatory markers.Data were obtained from 3044 men and women, aged ...
Koster, Annemarie, Bosma, Hans, Penninx, Brenda W.J.H., Newman, Anne B., Harris, Tamara B., Van Eijk, Jacques Th M., Kempen, Gertrudis I.J.M., Simonsick, Eleanor M., Johnson, Karen C., Rooks, Ronica N., Ayonayon, Hilsa N., Rubin, Susan M., Kritchevsky, Stephen B.   +12 more
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Can a Peripheral Blood Marker for Airway Neutrophilia Be Identified in Children with Bronchiectasis?

Children
Background: Airway bacterial infection and inflammation are often present in children with bronchiectasis. Systemic inflammation has also been reported.
Hendrik Willem Wiltingh, Julie Marchant, Anne Chang, Vikas Goyal   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Diagnostic role of inflammatory markers in patients with brucella

Medicine Science
Systemic inflammation plays a significant role in the initiation and advancement of chronic diseases. This study aimed to evaluate the prognostic utility of these indices in patients with brucellosis.
Filiz Kurklu Bozkir, Huseyin Erdal, Seval Sonmez Yildirim   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Potential protective effects of Quercetin on metalaxyl-induced oxidative stress, impaired liver functions and hepatotoxicity in rat [PDF]

Benha Veterinary Medical Journal, 2017
The purpose of this study was to investigate the protective and anti-inflammatory influence ofquercetin against metalaxyl fungicide induced liver toxicity and oxidative stress in rats. Forty twomale albino rats were divided into three equal groups. Group
Marwa Hassan, Mogda Mansour, Yakout El Senosi, Samy Hussein   +3 more
doaj   +1 more source