Results 51 to 60 of about 923,303 (263)

Correlation of sputum inflammatory markers with severity and blood inflammatory markers in bronchiectasis

Journal of Thoracic Disease
As a disease characterized by chronic neutrophilic inflammation, various sputum biomarkers have been investigated in the association with the severity and prognosis of bronchiectasis. However, there is lack of data on the association between sputum interleukin-1beta (IL-1β), interleukin-8 (IL-8) and tumor necrosis factor-alpha (TNF-α) levels at ...
Kwok, Wang Chun, Lau, Kui Kai, Teo, Kay Cheong, Ho, James Chung Man   +3 more
openaire   +2 more sources

Can a Peripheral Blood Marker for Airway Neutrophilia Be Identified in Children with Bronchiectasis?

Children
Background: Airway bacterial infection and inflammation are often present in children with bronchiectasis. Systemic inflammation has also been reported.
Hendrik Willem Wiltingh, Julie Marchant, Anne Chang, Vikas Goyal   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Association of Inflammatory Markers With Socioeconomic Status [PDF]

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2006
This study examines the association between socioeconomic status (SES) and inflammatory markers in well-functioning older adults and seeks to determine whether any association remains after adjusting for biomedical and behavioral factors typically related to elevated serum levels of inflammatory markers.Data were obtained from 3044 men and women, aged ...
Koster, Annemarie, Bosma, Hans, Penninx, Brenda W.J.H., Newman, Anne B., Harris, Tamara B., Van Eijk, Jacques Th M., Kempen, Gertrudis I.J.M., Simonsick, Eleanor M., Johnson, Karen C., Rooks, Ronica N., Ayonayon, Hilsa N., Rubin, Susan M., Kritchevsky, Stephen B.   +12 more
openaire   +4 more sources

Diagnostic role of inflammatory markers in patients with brucella

Medicine Science
Systemic inflammation plays a significant role in the initiation and advancement of chronic diseases. This study aimed to evaluate the prognostic utility of these indices in patients with brucellosis.
Filiz Kurklu Bozkir, Huseyin Erdal, Seval Sonmez Yildirim   +2 more
doaj   +1 more source

The inflammatory and hemostatic cardiovascular risk markers during acute hyperglycemic crisis in type 1 and type 2 diabetes [PDF]

Journal of Medical Biochemistry, 2019
Background: We analyzed cardiovascular inflammatory (Creactive protein (CRP), interleukin 6 (IL-6)), haemostatic (homocysteine) risk markers in lean and obese patients at admission and acute hyperglicemic crisis (AHC) resolving, involving diabetic ...
Popović Dragana, Lalić Katarina, Jotić Aleksandra, Miličić Tanja, Bogdanović Jelena, Đorđević Maja, Stanković Sanja, Jeremić Veljko, Lalić Nebojša M.   +8 more
doaj  

Diagnostic and Prognostic Significance of Inflammatory Markers in Lung Cancer-Associated Pleural Effusions

The International Journal of Biological Markers, 2010
Besides massive expression in inflammatory pleural effusions, inflammatory markers are also present in cancer-induced pleural effusions. Recent advances in cancer biology point to a role of inflammatory signaling in cancer and encourage reconsidering the
Jaromír Kotyza, David Havel, Jindra Vrzalová, Vlastimil Kulda, Miloš Pešek   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source