Results 131 to 140 of about 47,766 (237)

The Vitamin D Receptor Agonist BXL-01-0029 as a Potential New Pharmacological Tool for the Treatment of Inflammatory Myopathies

, 2013
Luigi Di Luigi, Mariangela Sottili, Cristina Antinozzi, Gabriella Barbara Vannelli, Francesco Romanelli, Valeria Riccieri, Guido Valesini, Andrea Lenzi, Clara Crescioli   +8 more
openalex   +2 more sources

SAT0352 Mortality in idiopathic inflammatory myopathy- results from a swedish nationwide population-based cohort study [PDF]

, 2017
C Dobloug, J Svensson, I Lundberg, M Holmqvist   +3 more
openalex   +1 more source

The Effect of Anti‐3‐Hydroxy‐3‐Methylglutaryl‐CoA Reductase (HMGCR) Human Autoantibodies on Muscle Regeneration in Mice

Muscle &Nerve, Volume 72, Issue 6, Page 1300-1308, December 2025.
ABSTRACT Introduction/Aims Anti‐3‐hydroxy‐3‐methylglutaryl‐CoA reductase (HMGCR) autoantibodies (aAbs) are pathogenic in immune‐mediated necrotizing myopathy (IMNM), partly through complement activation. C5 inhibition did not restore muscle strength in mice or patients with overt IMNM, suggesting additional pathogenic mechanisms.
Sarah Julien, Honorine Tomasevic, Thara Jaworski, Rachid Zoubairi, Jeremie Martinet, Laurent Drouot, Olivier Boyer   +6 more
wiley   +1 more source

Idiopathic inflammatory myopathy associated with Sjögren's disease: features of a distinct clinical entity. [PDF]

Front Immunol
Konen FF, Güzeloglu YE, Seeliger T, Jendretzky KF, Nay S, Grote-Levi L, Schwenkenbecher P, Gründges C, Ernst D, Witte T, Skripuletz T.   +10 more
europepmc   +1 more source

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, Volume 12, Issue 41, November 6, 2025.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

Idiopathic Inflammatory Myopathy-Molecular Mechanisms Underlying Its Pathogenesis and Physical Therapy Effects. [PDF]

Int J Mol Sci
Markowska A, Tarnacka B.
europepmc   +1 more source

Characterization of Novel POLG Mutations in Mitochondrial Encephalomyopathy: Pathogenic Validation and Comprehensive Genetic Profiling

Brain and Behavior, Volume 15, Issue 11, November 2025.
We report a 32‐year‐old female patient with SANDO syndrome (a subtype of mitochondrial encephalomyopathy), who carries two heterozygous POLG mutations: a novel c.3297G>C and a known c.1774C>T. The neuronal models expressing these mutations demonstrated mitochondrial dysfunction, thereby confirming their pathogenicity.
Fanjing Zhou, Jiang Chen, Tingzheng Zhang, Fengnan Niu, Jinglong Hu, Yun Xu, Meijuan Zhang   +6 more
wiley   +1 more source

FRI0455 Increasing incidence of adult idiopathic inflammatory myopathies: a ten-year uk epidemiological study [PDF]

, 2018
Matthew Parker, Alexander Oldroyd, Mark Roberts, Robert G. Cooper, Hector Chinoy   +4 more
openalex   +1 more source

Trends in idiopathic inflammatory myopathies: cross-sectional data from the German National Database [PDF]

, 2020
Katinka Albrecht, Dörte Huscher, Johanna Callhoff, Jutta Richter, Tobias Alexander, Jörg Henes, A. Zink   +6 more
openalex   +1 more source

Muscle fibre type shift in COPD: Adaptive, maladaptive or a bit of both?

Experimental Physiology, EarlyView.
Jacob Peter Hartmann, Hannah G. Caldwell, Ulrik Winning Iepsen   +2 more
wiley   +1 more source