Results 151 to 160 of about 48,191 (258)

Simultaneous Heart–Kidney Transplantation for Ebstein's Anomaly: A Viable Treatment Option in Latin America

Clinical Case Reports, Volume 14, Issue 8, August 2026.
Chest x‐ray showing a typical presentation of Ebstein anomaly with severe cardiomegaly and a prominent right atrium silhouette. ABSTRACT Simultaneous heart–kidney transplantation is a viable and effective treatment option for patients with congenital heart disease and advanced chronic kidney disease when both conditions threaten survival.
Edgar García‐Cruz, Andrea Luna‐Hernández, Jesús Alberto Blanco‐Hernández, Jorge Sánchez‐Nieto, Stephanie Teresa Angulo‐Cruzado, Karla Alejandra Pupiales‐Dávila, Carla Domínguez‐Pereyra, Reyna Moreno‐Ruíz, Carlos Antonio Villegas‐Chávez, Antonio Jordán‐Ríos, Daniel Manzur‐Sandoval, Victor Alejandro Quiroz‐Martínez, Francisco Martín Baranda‐Tovar   +12 more
wiley   +1 more source

Post-COVID-19 Inflammatory Myopathy With Dermatomyositis-Mixed Connective Tissue Disease (MCTD) Overlap Features and Epiglottitis: A Case Report. [PDF]

Cureus
Lorenz N, Mourad A, Weiderman G, Pulido JD.   +3 more
europepmc   +1 more source

Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei, Atefeh Taghavi, Amir R. Afshari, Farzaneh Davoudi, Elaheh Gheybi, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source

The SCRIM score: a clinical tool for cancer risk-stratification in patients with idiopathic inflammatory myopathy. [PDF]

Arthritis Res Ther
Kim YK, Pyo JY, Kim JY, Kim MJ, Yoo SJ, Park SY, Park JK, Lee EY, Lee YJ, Kang SW, Lee EB, Kim J, Park JW.   +12 more
europepmc   +1 more source

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong, Eunsoo Kim, Yong Sung Kim, Eunok Im   +3 more
wiley   +1 more source

Nerandomilast attenuates idiopathic inflammatory myopathy-associated interstitial lung disease via inhibiting proliferation and differentiation of B cells. [PDF]

Front Immunol
Liu Y, Hu Y, Se-Rigeleng, Yang Z, Liu X, Yu J, Li H, Gu S, Yang W, Yang C, Zhou H, He Y, Kong C, Gu X, Li X.   +14 more
europepmc   +1 more source

The Therapeutic Potential of H2S‐Releasing Platforms in Cardiovascular Applications

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.
The Therapeutic Potential of H2S‐Releasing Platforms. ABSTRACT Once known as a toxic gas, hydrogen sulfide (H2S) is now making its way into many therapeutic applications. Similar to its other fellow endogenous gasotransmitters, nitric oxide and carbon monoxide, H2S is a small gas with a short half‐life, making it extremely capable of penetrating ...
Tia N. Shorter, Elizabeth J. Brisbois
wiley   +1 more source

Characterization of Muscle Tissue Cell Diversity and Clinical Implications in Idiopathic Inflammatory Myopathy. [PDF]

J Cachexia Sarcopenia Muscle
Zhu H, Xiao Y, Xie S, Meng Q, Ding T, Huang T, Liu D, Liu S, Zhang X, Zhang H, Luo H.   +10 more
europepmc   +1 more source

Dnajb5 From Antarctic Fish Reveals a Redox‐Sensitive Mechanism Coordinating Muscle Regeneration via mTORC1 and HDAC4

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Dnajb5, a member of the heat shock protein family, has not been previously reported to play a role in muscle differentiation. We identify Dnajb5 as a negative regulator of myogenesis via mammalian target of rapamycin (mTOR) and histone deacetylase 4 (HDAC4) signalling, functioning as a central controller of muscle growth and ...
Sun‐Hee Cho, Min‐Kyung Choi, Mi‐Ock Baek, Hyeon‐Hee Son, Binh Thanh Nguyen, Min‐Jung Kang, Il‐Chan Kim, Jin‐Hyoung Kim, Mee‐Sup Yoon   +8 more
wiley   +1 more source

Cigarette Smoke‐Exposed Alveolar Epithelial Cell‐Derived Exosomes Exacerbate Skeletal Muscle Dysfunction Through HDAC2 Signalling

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle dysfunction (SMD) is a common extrapulmonary complication of chronic obstructive pulmonary disease (COPD). Histone deacetylase 2 (HDAC2) is closely involved in the suppression of inflammatory transcription and is progressively reduced during COPD progression.
Chao Li, MingZhi Ou, Gang Jiang, GuiXian Zheng, YongLiang Jiang   +4 more
wiley   +1 more source