Results 171 to 180 of about 1,059,580 (243)

Expression of COL6A1 in Tumor Matrix of Cholangiocarcinoma and Its Mechanism of Tumor Progression

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Cholangiocarcinoma (CCA), a malignant tumor originating from the bile duct epithelial cells, is characterized by aggressive invasion and poor prognosis. Abnormal remodeling of the tumor microenvironment plays a pivotal role in its disease progression.
Weibin Zhang   +13 more
wiley   +1 more source

USP25 stabilises GLI1 through K48‐linked deubiquitination within a reciprocal regulatory circuit in osteoarthritis models

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
GLI1‐centred USP25‐GLI1 reciprocal regulation in OA‐relevant models. Hedgehog/GLI1 signalling transcriptionally reinforces USP25 expression, while USP25 deubiquitinates and stabilises GLI1. This reciprocal circuit is associated with inflammatory and cartilage‐catabolic changes in the tested models.
Qian Zhang   +4 more
wiley   +1 more source

Hong Kong Poison Information Centre: Annual report 2022

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 5, October 2026.
Abstract Background The Hong Kong Poison Information Centre (HKPIC) has been providing consultation services to healthcare professionals and collecting epidemiological data on poisoning in Hong Kong since 2005. Objective To analyse and report the poisoning data from HKPIC in 2022.
Tin Yat Anthony Chow   +4 more
wiley   +1 more source

Idiopathic inflammatory myopathy associated with Sjögren's disease: features of a distinct clinical entity. [PDF]

open access: yesFront Immunol
Konen FF   +10 more
europepmc   +1 more source

Rev‐erb‐α in Skeletal Muscle Adaptation: Integrating Circadian Control Mechanisms and Exercise Dynamic Responses

open access: yesJournal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Circadian rhythms orchestrate a host of biological processes in a time‐dependent manner to maintain homeostasis in response to exercise. Within this framework, Rev‐erb‐α, an intracellular nuclear receptor and transcriptional regulator, transcends its role in circadian rhythms to drive myogenesis, muscle remodeling, primary metabolism, and ...
Ivo Vieira de Sousa Neto   +7 more
wiley   +1 more source

Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Urolithin A (UA) and urolithin B (UB) are gut microbiota‐derived metabolites of ellagitannins reported to influence mitochondrial function, inflammation and muscle metabolism. Their comparative transcriptomic effects in human skeletal muscle cells remain undefined.
Yves Henrotin   +8 more
wiley   +1 more source

Brachio-cervical inflammatory myopathy: multilevel clinical, histopathological and multi-omic analyses of a syndrome variably associated with systemic sclerosis. [PDF]

open access: yesActa Neuropathol
Kleefeld F   +27 more
europepmc   +1 more source

Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi   +9 more
wiley   +1 more source

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