Results 141 to 150 of about 47,766 (237)

Tacrolimus Trough Concentration‐Escalating Bipartite Therapy (Glucocorticoids Combined With Tacrolimus) for Refractory MDA5 Antibody‐Positive Clinically Amyopathic Dermatomyositis With Rapidly Progressive Interstitial Pneumonia

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 11, November 2025.
ABSTRACT Objective This study aimed to determine the outcomes of patients that have refractory anti‐melanoma differentiation‐associated gene 5 (MDA5) antibody‐positive clinically amyopathic dermatomyositis with rapidly progressive interstitial pneumonia treated with tacrolimus trough concentration‐escalating bipartite therapy (glucocorticoids combined ...
Anji Xiong   +10 more
wiley   +1 more source

The SCRIM score: a clinical tool for cancer risk-stratification in patients with idiopathic inflammatory myopathy. [PDF]

open access: yesArthritis Res Ther
Kim YK   +12 more
europepmc   +1 more source

Chimeric Antigen Receptor T‐Cell Therapy and Autoimmune Diseases in the Nervous System

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 11, November 2025.
ABSTRACT Introduction Chimeric antigen receptor T‐cell (CAR‐T) therapy, a revolutionary immunotherapy originally developed for hematologic malignancies, has recently gained attention for its potential in treating autoimmune diseases. Increasing evidence suggests that CAR‐T cells can precisely target pathogenic immune populations, offering durable ...
Shun‐yu Yao   +11 more
wiley   +1 more source

Integrated Multiomics Analysis and Mendelian Randomization Identify SIRT1 as a Pivotal Aging‐Associated Gene in Meningioma

open access: yesIUBMB Life, Volume 77, Issue 11, November 2025.
ABSTRACT Meningiomas (MGMs) are the most prevalent benign intracranial tumors in adults, with incidence markedly increasing with age, underscoring the need to explore aging‐associated molecular mechanisms. In this study, we integrated transcriptomic datasets (GSE43290, GSE54934, GSE77259, and GSE183655) from the GEO database and aging‐related genes ...
Guangyu Du   +7 more
wiley   +1 more source

Exploring a Circulating miRNA Signature for PMM2‐CDG: Initial Insights Toward Diagnosis, Stratification, and Monitoring

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Phosphomannomutase deficiency (PMM2‐CDG) is the most common congenital disorder of glycosylation, characterized by variable early‐onset neurological (hypotonia, cerebellar syndrome, developmental delay) and multi‐organ manifestations. Although several clinical trials are ongoing, current biomarkers lack prognostic or monitoring utility ...
Florencia Epifani   +14 more
wiley   +1 more source

Anti-U3 ribonucleoprotein antibody-positive inflammatory myopathy: a case report [PDF]

open access: gold, 2016
Kenya Murata   +4 more
openalex   +1 more source

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