Objective Interstitial lung disease (ILD) is common in idiopathic inflammatory myositis (IIM), particularly in antisynthetase syndrome (ASyS), antimelanoma differentiation‐associated protein 5 (anti‐MDA5) syndrome, and scleromyositis. ILD can progress despite resolution of extrapulmonary symptoms, termed postmyopathic progressive pulmonary fibrosis ...
Julia Clark +5 more
wiley +1 more source
Utilization of Rehabilitation Services After Idiopathic Inflammatory Myopathy Diagnosis: A Retrospective Cohort Assessment in the United States. [PDF]
Allenzara A +7 more
europepmc +1 more source
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim +16 more
wiley +1 more source
Editorial: New insights into the pathogenesis of idiopathic inflammatory myopathy. [PDF]
Ascherman DP.
europepmc +1 more source
Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov +8 more
wiley +1 more source
The SCRIM score: a clinical tool for cancer risk-stratification in patients with idiopathic inflammatory myopathy. [PDF]
Kim YK +12 more
europepmc +1 more source
Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley +1 more source
Characterization of Muscle Tissue Cell Diversity and Clinical Implications in Idiopathic Inflammatory Myopathy. [PDF]
Zhu H +10 more
europepmc +1 more source
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar +5 more
wiley +1 more source
Anti-mitochondrial M2 antibody links to cardiac involvement and immune-mediated inflammatory myopathy-like pathology in myositis. [PDF]
Pang Y +19 more
europepmc +1 more source

