Results 41 to 50 of about 70,263 (344)
Idiopathic inflammatory myopathy and non-coding RNA
Idiopathic inflammatory myopathies (IIMs) are common autoimmune diseases that affect skeletal muscle quality and function. The lack of an early diagnosis and treatment can lead to irreversible muscle damage.
Yang Yang +5 more
doaj +1 more source
Major Histocompatibility Complex I and II Expression and Lymphocytic Subtypes in Muscle of Horses with Immune-Mediated Myositis. [PDF]
BackgroundMajor histocompatibility complex (MHC) I and II expression is not normally detected on sarcolemma, but is detected with lymphocytic infiltrates in immune-mediated myositis (IMM) of humans and dogs and in dysferlin-deficient muscular dystrophy ...
Barnes, N +6 more
core +1 more source
Inflammatory myopathies such as dermatomyositis and polymyositis are well-recognized paraneoplastic syndromes. Little is known, however, about necrotizing myopathies in association with cancer.
Susanne Wegener +4 more
doaj +1 more source
Gene Expression Profiles of Inflammatory Myopathies
The simultaneous expression of 10,000 genes was measured, using Affymetrix GeneChip microarrays, in muscle specimens from 45 patients with various myopathies (dystrophy, congenital myopathy, and inflammatory myopathy) examined at Brigham and Women’s ...
J Gordon Millichap
doaj +1 more source
Inflammation affects various organs of the human body, including skeletal muscle. Phlorotannins are natural biologically active substances found in marine brown algae and exhibit anti-inflammatory activities.
Seo-Young Kim +5 more
doaj +1 more source
A Case Report of Statin-Induced Immune-Mediated Necrotizing Myopathy Treatment Challenges
Statin-induced necrotizing autoimmune myopathy is an immune-mediated necrotizing myopathy related to the use of statins. It is a very rare disease, which usually presents with proximal muscle weakness and frank elevation in creatine kinase levels ...
Anwar I. Joudeh +5 more
doaj +1 more source
Children’s Multisystem inflammatory syndrome with myopathy
This report describes a case of multisystem inflammatory syndrome in a child that evolved with a pattern of toxic shock syndrome with coronary artery ectasia and neurological involvement, documented by magnetic resonance imaging, with changes in the ...
Zina Maria Almeida de Azevedo +12 more
doaj +1 more source
Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial) [PDF]
Introduction: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in ...
Barnett, A. H. +11 more
core +3 more sources
Murine models of idiopathic inflammatory myopathy
Idiopathic inflammatory myopathies (IIMs) are characterized by inflammation of muscles and other organs. Several myositis-specific autoantibodies (MSAs) have been identified in IIMs and were found to be associated with distinct clinical features ...
Risa Konishi +2 more
doaj +1 more source
A Path to Prediction of Outcomes in Juvenile Idiopathic Inflammatory Myopathy
Humans have an innate desire to observe and subsequently dissect an event into component pieces in an effort to better characterize the event. We then examine these pieces individually and in combinations using this information to determine the outcome ...
Ann Marie Reed +3 more
doaj +1 more source

