Abstract Objectives Methotrexate (MTX) is frequently prescribed in paediatric inflammatory bowel disease (IBD), with routine laboratory monitoring to detect adverse events (AEs), such as hepatotoxicity and myelotoxicity. However, data on the incidence and predictors of these AEs remain limited.
Eva Vermeer +7 more
wiley +1 more source
Advances in the Management of Pediatric Inflammatory Bowel Disease: From Biologics to Small Molecules. [PDF]
Mucci B +5 more
europepmc +1 more source
Incidence of acute severe infusion reactions to infliximab depends on definition used rather than assay: authors’ reply [PDF]
Casper Steenholdt +5 more
openalex +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
The Potential of High-Density Lipoprotein as a Predictive Biomarker for Infliximab Efficacy in Crohn's Disease. [PDF]
Tang K +6 more
europepmc +1 more source
TNF Inhibitor‐Induced Sarcoidosis‐Like Lesions in Inflammatory Bowel Disease
ABSTRACT Background While tumor necrosis factor (TNF) inhibitors can induce paradoxical reactions, sarcoidosis‐like disease has hardly been reported so far. This study aimed to describe the epidemiological, diagnostic and therapeutic features of TNF inhibitor‐induced sarcoidosis‐like lesions in patients with inflammatory bowel disease.
Zlata Chkolnaia +12 more
wiley +1 more source
Infliximab-Induced Autoimmune Phenomenon in an Adolescent With Ulcerative Colitis: Drug-Induced Lupus vs Inflammatory Myositis. [PDF]
Bakshi N, Kardouh MS, Kriem J.
europepmc +1 more source
Alopecia areata in a patient using infliximab: new insights into the role of tumor necrosis factor on human hair follicles [PDF]
Leila Ettefagh, Paradi Mirmirani
openalex +1 more source
ABSTRACT Background Bowel urgency (BU) is reported by over 80% of patients with ulcerative colitis (UC) and 60% of those with Crohn's disease (CD). However, the impact of advanced therapies on BU has not been consistently evaluated. Objectives To assess the effect of advanced therapies on BU improvement in patients with UC and CD.
Ferdinando D'Amico +17 more
wiley +1 more source
Implementation and Evaluation of a Standard Operating Procedure for Pediatric Infliximab Infusions
Maureen M. Kelly +4 more
openalex +1 more source

