Results 81 to 90 of about 919,130 (221)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Identifying influential nodes in bipartite networks using the clustering coefficient
, 2014 The identification of influential nodes in complex network can be very challenging. If the network has a community structure, centrality measures may fail to identify the complete set of influential nodes, as the hubs and other central nodes of the ...
Jessica Liebig (8081897) +1 more
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Identifying Influential Nodes in Community Networks
Real systems often own strong community attributes Considering the high clustering and the heterogeneity of communities a community based Clustering LeaderRank CCL Algorithm is proposed to identify influential nodes in community networks Nodes are ranked
Wang, X +5 more
core +1 more source
A comprehensive scheme for reconfigurable energy-aware wireless sensor nodes
, 2010 Wireless sensor nodes are devices that perform measurements (of parameters such as temperature or vibration) and communicate over a wireless medium. A key benefit is that they can operate autonomously.
Weddell, Alexander Stewart
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Discovering Influential Nodes from Social Trust Network [PDF]
, 2012 The goal of viral marketing is that, by the virtue of mouth to mouth word spread, a small set of influential customers can influence greater number of customers. Influence maximization (IM) task is to discover such influential nodes (or customers) from a
Ahmed, Sabbir
core +1 more source
Identifying Influential Nodes: The Overlapping Modularity Vitality Framework
, 2023 International audienceThis paper proposes an Overlapping Modularity Vitality framework for identifying influential nodes in networks with overlapping community structures.
Rajeh, Stephany, Cherifi, Hocine
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source