Results 71 to 80 of about 919,130 (221)

Identifying Influential Nodes in Complex Networks Based on Local Neighbor Contribution

IEEE Access, 2019
The identification of influential nodes in complex networks has been widely used to suppress rumor dissemination and control the spread of epidemics and diseases.
Jinying Dai, Bin Wang, Jinfang Sheng, Zejun Sun, Faiza Riaz Khawaja, Aman Ullah, Dawit Aklilu Dejene, Guihua Duan   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Identifying Influential Nodes in Complex Networks Based on Local Effective Distance

Information, 2019
With the rapid development of Internet technology, the social network has gradually become an indispensable platform for users to release information, obtain information, and share information.
Junkai Zhang, Bin Wang, Jinfang Sheng, Jinying Dai, Jie Hu, Long Chen   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Centrality in modular networks

EPJ Data Science, 2019
Identifying influential nodes in a network is a fundamental issue due to its wide applications, such as accelerating information diffusion or halting virus spreading.
Zakariya Ghalmane, Mohammed El Hassouni, Chantal Cherifi, Hocine Cherifi   +3 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Identifying influential nodes in complex networks for network immunization

, 2014
Identifying influential nodes is of theoretical significance in network immunization which is one of important methods to prevent virus propagation through protecting the influential nodes in a network.
C Gao (81541), N Shi (13585726), L Zhong (13393722), Zili Zhang (13101534), J Huang (3663847)   +4 more
core  

Critical node detection in temporal social networks, based on global and semi-local centrality measures.

PLoS ONE
Nodes that play strategic roles in networks are called critical or influential nodes. For example, in an epidemic, we can control the infection spread by isolating critical nodes; in marketing, we can use certain nodes as the initial spreaders aiming to ...
Zahra Farahi, Rooholah Abedian, Luis E C Rocha, Ali Kamandi   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source