Results 61 to 70 of about 919,130 (221)

On influential nodes tracking in dynamic social networks

, 2015
Real world marketing campaign utilizing the word-of-mouth effect usually lasts a long time, where multiple sets of influential users need to be mined and targeted at different times to fully utilize the power of viral marketing.
Chen, Xiaodong, Xie, Kunqing, Xiaodong Chen, Kunqing Xie, Guojie Song, He, Xinran, Xinran He, Song, Guojie   +7 more
core   +1 more source

Temporal Sequence of Retweets Help to Detect Influential Nodes in Social Networks [PDF]

, 2019
Identification of influential users in online social networks allows to facilitate efficient information diffusion to a large part of the network and thus benefiting diverse applications including viral marketing, disease control, and news dissemination.
Lambiotte, Renaud, Bivas Mitra, Martin Gueuning, Bhowmick, Ayan Kumar, Bhowmick, A, Lambiotte, R, Mitra, Bivas, Mitra, B, Ayan Kumar Bhowmick, GUEUNING, Martin, Gueuning, M, Jean-Charles Delvenne, Delvenne, Jean Charles, Renaud Lambiotte, Delvenne, J-C, Delvenne, Jean-Charles   +15 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Tracking Influential Nodes in Time-Decaying Dynamic Interaction Networks

, 2019
Identifying influential nodes that can jointly trigger the maximum influence spread in networks is a fundamental problem in many applications such as viral marketing, online advertising, and disease control.
Zhang, Xiangliang, Shuo Shang, Shang, Shuo, Junzhou Zhao, John C.S. Lui, Zhao, Junzhou, Lui, John C.S., Pinghui Wang, Wang, Pinghui, Xiangliang Zhang   +9 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Locating influential nodes in hypergraphs via fuzzy collective influence [PDF]

Complex contagion phenomena, such as the spread of information or contagious diseases, often occur among the population due to higher-order interactions between individuals.
Yu, Xiaoyan, Sun, Gui-Quan, Zhang, Su-Su, Liu, Chuang, Zhan, Xiu-Xiu   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source