Results 31 to 40 of about 9,115,931 (294)

Insights into Genetic Characteristics and Virological Features of Endemic Avian Influenza A (H9N2) Viruses in Egypt from 2017–2021

Viruses, 2022
From 2010 to 2013, genotype I avian influenza A(H9N2) viruses of the G1-lineage were isolated from several poultry species in Egypt. In 2014, novel reassortant H9N2 viruses were detected in pigeons designated as genotype II.
Mohamed El Sayes, Ahmed Kandeil, Yassmin Moatasim, Ahmed El Taweel, Adam Rubrum, Omnia Kutkat, Mina Nabil Kamel, Rebecca Badra, Ahmed B. Barakat, Pamela P. McKenzie, Rabeh El-Shesheny, Richard J. Webby, Ghazi Kayali, Mohamed Ahmed Ali   +13 more
doaj   +1 more source

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

Science Translational Medicine, 2019
A next-generation, broad-spectrum, orally efficacious influenza A and B virus inhibitor is associated with a high genetic resistance barrier. Treating flu, escaping resistance Influenza viruses can cause severe illness and death.
M. Toots, Jeong-Joong Yoon, R. Cox, M. Hart, Zachary M. Sticher, Negar Makhsous, R. Plesker, Alec H Barrena, Prabhakar Reddy, Deborah G. Mitchell, Ryan C. Shean, Gregory R. Bluemling, A. Kolykhalov, A. Greninger, M. Natchus, G. Painter, Richard K. Plemper   +16 more
semanticscholar   +1 more source

Alarming situation of emerging H5 and H7 avian influenza and effective control strategies

Emerging Microbes and Infections, 2022
Avian influenza viruses continue to present challenges to animal and human health. Viruses bearing the hemagglutinin (HA) gene of the H5 subtype and H7 subtype have caused 2634 human cases around the world, including more than 1000 deaths.
Jianzhong Shi, Xianying Zeng, Pengfei Cui, Cheng Yan, Hualan Chen   +4 more
semanticscholar   +1 more source

Influenza research database: an integrated bioinformatics resource for influenza research and surveillance. [PDF]

, 2012
BackgroundThe recent emergence of the 2009 pandemic influenza A/H1N1 virus has highlighted the value of free and open access to influenza virus genome sequence data integrated with information about other important virus characteristics.DesignThe ...
Baumgarth, Nicole, Deitrich, Jon, García-Sastre, Adolfo, Hunt, Victoria, Klem, Edward, Kumar, Sanjeev, Larsen, Christopher N, Macken, Catherine, Noronha, Jyothi, Pickett, Brett E, Ramsey, Alvin, Scheuermann, Richard H, Squires, R Burke, Suarez, David, Zaremba, Sam, Zhang, Yun, Zhou, Liwei   +16 more
core   +1 more source

The role of platelets in mediating a response to human influenza infection

Nature Communications, 2019
Influenza infection increases the incidence of myocardial infarction but the reason is unknown. Platelets mediate vascular occlusion through thrombotic functions but are also recognized to have immunomodulatory activity.
Milka Koupenova, Heather A. Corkrey, O. Vitseva, Giorgia Manni, Catherine J. Pang, L. Clancy, C. Yao, J. Rade, D. Levy, Jennifer P. Wang, R. Finberg, E. Kurt-Jones, J. Freedman   +12 more
semanticscholar   +1 more source

Emerging viral respiratory tract infections—environmental risk factors and transmission [PDF]

, 2014
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Charrel, Remi N., Gautret, Philippe, Gray, Gregory C., Memish, Ziad A., Odezulu, Nnanyelugo G., Zumla, Alimuddin   +6 more
core   +1 more source

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

Science, 2019
Alternative influenza target There is a pressing need for a broadly protective influenza vaccine that can neutralize this constantly varying, deadly virus. Stadlbauer et al.
D. Stadlbauer, Xueyong Zhu, Meagan McMahon, J. Turner, Teddy J. Wohlbold, A. Schmitz, Shirin Strohmeier, Wenli Yu, Raffael Nachbagauer, P. Mudd, I. Wilson, A. Ellebedy, F. Krammer   +12 more
semanticscholar   +1 more source

Results from the centers for disease control and prevention's predict the 2013-2014 Influenza Season Challenge [PDF]

, 2016
Background: Early insights into the timing of the start, peak, and intensity of the influenza season could be useful in planning influenza prevention and control activities.
Allen, Christopher, Alper, David, Aman, Susan, Anil Kumar, V. S., Aslam, Anoshã, Bakach, Iurii, Barrett, Chris, BASAGNI, Stefano, Biggerstaff, Matthew, Bisset, Keith, Broniatowski, David, Brooks, Logan, Brownstein, John S., Butler, Patrick, Chakraborty, Prithwish, Chandra, Priyadarshini, Chen, Jiangzhuo, Del Valle, Sara Y., Deshpande, Alina, Dredze, Mark, Eggo, Rosalind, Eubank, Stephen, Fairchild, Geoffrey, Farrow, David, Finelli, Lyn, Fox, Spencer, Fung, Isaac Chun Hai, Gambhir, Manoj, Generous, Nicholas, GESUALDO, Francesco, Goldstein, Ed, Hao, Yi, Henderson, Jette, Hickman, Kyle S., Hickmann, Kyle S., Hyman, James M., Hyun, Sangwon, Karspeck, Alicia, Kaup, Hemchandra, Khadivi, Pejman, Krishnan, Ramesh, Laskowski, Kathy, Lewis, Bryan, Lipsitch, Marc, Lum, Kristian, Madhavan, Satish, Marathe, Madhav, Markar, Ashirwad, Mekaru, Sumiko R., Meyers, Lauren Ancel, Nagel, Anna, Nsoesie, Elaine O., Pashley, Bryanne, Paul, Michael, PERRA, NICOLA, Priedhorsky, Reid, Ramakrishnan, Anurekha, Ramakrishnan, Naren, Rosenfeld, Roni, Scarpino, Sam, Schaible, Braydon J., Scott, James, Sexton, Jessica K., Shaman, Jeffrey, Singh, Bismark, Srinivasan, Ravi, STILO, GIOVANNI, Tibshirani, Ryan J., Tozzi, Alberto E., Tse, Zion Tsz Ho, Tsou, Ming Hsiang, VELARDI, Paola, Vespignani, Alessandro, Yang, Wan, Ying, Yuchen, Zhang, Qian   +75 more
core   +1 more source

Polymer-stabilized sialylated nanoparticles : synthesis, optimization, and differential binding to influenza hemagglutinins [PDF]

, 2020
During influenza infection, hemagglutinins (HAs) on the viral surface bind to sialic acids on the host cell's surface. While all HAs bind sialic acids, human influenza targets terminal α2,6 sialic acids and avian influenza targets α2,3 sialic acids.
Baker, Alexander, Gibson, Matthew I., Richards, Sarah-Jane, Walker, Marc   +3 more
core   +2 more sources

Potent Antiviral Activity of Vitamin B12 against Severe Acute Respiratory Syndrome Coronavirus 2, Middle East Respiratory Syndrome Coronavirus, and Human Coronavirus 229E

Microorganisms, 2023
Repurposing vitamins as antiviral supporting agents is a rapid approach used to control emerging viral infections. Although there is considerable evidence supporting the use of vitamin supplementation in viral infections, including severe acute ...
Yassmin Moatasim, Omnia Kutkat, Ahmed M. Osman, Mokhtar R. Gomaa, Faten Okda, Mohamed El Sayes, Mina Nabil Kamel, Mohamed Gaballah, Ahmed Mostafa, Rabeh El-Shesheny, Ghazi Kayali, Mohamed A. Ali, Ahmed Kandeil   +12 more
doaj   +1 more source