Results 51 to 60 of about 537,845 (300)

Results from the centers for disease control and prevention's predict the 2013-2014 Influenza Season Challenge [PDF]

open access: yes, 2016
Background: Early insights into the timing of the start, peak, and intensity of the influenza season could be useful in planning influenza prevention and control activities.
Allen, Christopher   +75 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Enhanced passive surveillance of influenza vaccination in England, 2016−2017– an observational study using an adverse events reporting card

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Influenza is a major public health burden, mainly prevented by vaccination. Recommendations on influenza vaccine composition are updated annually and constant benefit-risk monitoring is therefore needed.
Simon de Lusignan   +8 more
doaj   +1 more source

Vacina contra o vírus da influenza e mortalidade por doenças cardiovasculares na cidade de São Paulo Vacuna contra el virus de la Influenza y mortalidad por enfermedades cardiovasculares en la Ciudad de São Paulo Vaccination against the influenza virus and mortality due to cardiovascular diseases in the city of Sao Paulo

open access: yesArquivos Brasileiros de Cardiologia, 2009
FUNDAMENTO: A influência da vacinação contra o vírus da gripe na mortalidade por doenças cardiovasculares (DCV) é controversa. OBJETIVO: Analisar a mortalidade por DCV antes e depois do início da vacinação contra a gripe na cidade de São Paulo.
Antonio de Padua Mansur   +2 more
doaj   +1 more source

Mortality due to respiratory diseases in the elderly after influenza vaccination campaigns in the Federal District, Brazil, 1996-2009 [PDF]

open access: yesJornal Brasileiro de Pneumologia, 2013
OBJECTIVE: To compare mortality rates due to respiratory diseases among elderly individuals residing in the Federal District of Brasília, Brazil, prior to and after the implementation of a national influenza vaccination campaign. METHODS: This was an
Francisca Magalhães Scoralick   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Impact of Individual Viral Gene Segments from Influenza A/H5N8 Virus on the Protective Efficacy of Inactivated Subtype-Specific Influenza Vaccine

open access: yesPathogens, 2021
Since its emergence in 2014, the highly pathogenic avian influenza H5N8 virus has continuously and rapidly spread worldwide in the poultry sector resulting in huge economic losses.
Yassmin Moatasim   +10 more
doaj   +1 more source

Predicting Avian Influenza Co-Infection with H5N1 and H9N2 in Northern Egypt. [PDF]

open access: yes, 2016
Human outbreaks with avian influenza have been, so far, constrained by poor viral adaptation to non-avian hosts. This could be overcome via co-infection, whereby two strains share genetic material, allowing new hybrid strains to emerge. Identifying areas
Ali, Mohamed A   +5 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Safety and Immunogenicity of Betuvax-CoV-2, an RBD-Fc-Based SARS-CoV-2 Recombinant Vaccine: Preliminary Results of the First-in-Human, Randomized, Double-Blind, Placebo-Controlled Phase I/II Clinical Trial

open access: yesVaccines, 2023
COVID-19, being a life-threatening infection that evolves rapidly, remains a major public health concern calling for the development of vaccines with broad protection against different pathogenic strains and high immunogenicity.
Aleksandr V. Kudriavtsev   +15 more
doaj   +1 more source

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