Influenza vaccination for immunocompromised patients: systematic review and meta-analysis from a public health policy perspective. [PDF]
Immunocompromised patients are vulnerable to severe or complicated influenza infection. Vaccination is widely recommended for this group. This systematic review and meta-analysis assesses influenza vaccination for immunocompromised patients in terms of ...
Kerac, Marko +143 more
core +4 more sources
Existing influenza surveillance system is constantly improved to obtain comprehensive information for understanding of continuously changing situation with the influenza, which is a consequence of the highest variability of the pathogen, its ability to ...
A. A. Sominina +3 more
doaj +1 more source
Antiviral responses by Swine primary bronchoepithelial cells are limited compared to human bronchoepithelial cells following influenza virus infection. [PDF]
Swine generate reassortant influenza viruses because they can be simultaneously infected with avian and human influenza; however, the features that restrict influenza reassortment in swine and human hosts are not fully understood.
Mary J Hauser +5 more
doaj +1 more source
Influenza A H5N1 Replication Sites in Humans
Tissue tropism and pathogenesis of influenza A virus subtype H5N1 disease in humans is not well defined. In mammalian experimental models, H5N1 influenza is a disseminated disease. However, limited previous data from human autopsies have not shown evidence of virus dissemination beyond the lung.
Uiprasertkul, M +9 more
openaire +4 more sources
Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K. +35 more
core +1 more source
Qualitative evaluation of a molecular point-of-care testing study for influenza in UK primary care
Background: Influenza contributes to the surge in winter infections and the consequent winter pressures on the health service. Molecular point-of-care testing (POCT) for influenza may improve patient management by providing rapid and accurate clinical ...
Charis Xuan Xie +12 more
doaj +1 more source
Avian Influenza virus glycoproteins restrict virus replication and spread through human airway epithelium at temperatures of the proximal airways. [PDF]
Transmission of avian influenza viruses from bird to human is a rare event even though avian influenza viruses infect the ciliated epithelium of human airways in vitro and ex vivo.
Margaret A Scull +7 more
doaj +1 more source
Advancing Treatment Options for Influenza: Challenges With the Human Influenza Challenge [PDF]
Current therapeutic options for the treatment of influenza virus infections are limited. Only 2 classes of agents have licensed products, neuraminidase (NA) inhibitors and M2 inhibitors, and only NA inhibitors are active against currently circulating seasonal viruses.
Alicia M, Fry +2 more
openaire +2 more sources
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase [PDF]
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Russell, Rupert James Martin +35 more
core +1 more source
The analysis of the spatial-temporal distribution of influenza data weekly to WHO data in the summer of 2015 in the countries of the Southern and Northern hemispheres It is shown that in the Southern hemisphere registered a moderate influenza epidemics ...
O. L. Kiselev +3 more
doaj +1 more source

