Results 71 to 80 of about 8,955,500 (341)

Impact of Individual Viral Gene Segments from Influenza A/H5N8 Virus on the Protective Efficacy of Inactivated Subtype-Specific Influenza Vaccine

Pathogens, 2021
Since its emergence in 2014, the highly pathogenic avian influenza H5N8 virus has continuously and rapidly spread worldwide in the poultry sector resulting in huge economic losses.
Yassmin Moatasim, Ahmed Kandeil, Ahmed Mostafa, Omnia Kutkat, Mohamed El Sayes, Ahmed N. El Taweel, Maha AlKhazindar, Elsayed T. AbdElSalam, Rabeh El-Shesheny, Ghazi Kayali, Mohamed A. Ali   +10 more
doaj   +1 more source

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection

Journal of Infectious Diseases, 2018
Using ferret models of influenza virus and human respiratory syncytial virus (hRSV), we demonstrate that infection with influenza virus can prevent or limit infection with hRSV, whereas infection with hRSV reduces morbidity attributed to influenza virus ...
K. Chan, Louise A. Carolan, D. Korenkov, J. Druce, J. McCaw, P. Reading, I. Barr, K. Laurie   +7 more
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Porcine innate and adaptative immune responses to influenza and coronavirus infections [PDF]

, 2006
Both innate and adaptative immune responses contribute to the control of infectious diseases, including by limiting the spreading of zoonotic diseases from animal reservoirs to humans.
Asselin-Paturel, Baudoux, BERNARD CHARLEY, Brim, Charley, Charley, Charley, Chen, Chinsangaram, Corthier, Fitzgerald-Bocarsly, Guzylack-Piriou, Heinen, KRISTIEN VAN REETH, La Bonnardière, Laude, Laude, Le Bon, Lim, Liu, Palese, Peiris, Pestka, Riffault, Riffault, Riffault, Rothenfusser, SABINE RIFFAULT, Saif, Siegal, Summerfield, Tu, Tudor, Van Reeth, Van Reeth, van Reeth   +35 more
core   +2 more sources

Polymer-stabilized sialylated nanoparticles : synthesis, optimization, and differential binding to influenza hemagglutinins [PDF]

, 2020
During influenza infection, hemagglutinins (HAs) on the viral surface bind to sialic acids on the host cell's surface. While all HAs bind sialic acids, human influenza targets terminal α2,6 sialic acids and avian influenza targets α2,3 sialic acids.
Baker, Alexander, Gibson, Matthew I., Richards, Sarah-Jane, Walker, Marc   +3 more
core   +2 more sources

Human mobility and the spatial transmission of influenza in the United States

PLoS Comput. Biol., 2017
Seasonal influenza epidemics offer unique opportunities to study the invasion and re-invasion waves of a pathogen in a partially immune population. Detailed patterns of spread remain elusive, however, due to lack of granular disease data.
V. Charu, S. Zeger, J. Gog, O. Bjørnstad, S. Kissler, L. Simonsen, B. Grenfell, C. Viboud   +7 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Mortality due to respiratory diseases in the elderly after influenza vaccination campaigns in the Federal District, Brazil, 1996-2009 [PDF]

Jornal Brasileiro de Pneumologia, 2013
OBJECTIVE: To compare mortality rates due to respiratory diseases among elderly individuals residing in the Federal District of Brasília, Brazil, prior to and after the implementation of a national influenza vaccination campaign. METHODS: This was an
Francisca Magalhães Scoralick, Luciana Paganini Piazzolla, Liana Laura Pires, Cleudsom Neri, Wladimir Kummer de Paula   +4 more
doaj   +1 more source

Safety and Immunogenicity of Betuvax-CoV-2, an RBD-Fc-Based SARS-CoV-2 Recombinant Vaccine: Preliminary Results of the First-in-Human, Randomized, Double-Blind, Placebo-Controlled Phase I/II Clinical Trial

Vaccines, 2023
COVID-19, being a life-threatening infection that evolves rapidly, remains a major public health concern calling for the development of vaccines with broad protection against different pathogenic strains and high immunogenicity.
Aleksandr V. Kudriavtsev, Anna V. Vakhrusheva, Nickolay A. Kryuchkov, Maria E. Frolova, Konstantin A. Blagodatskikh, Taras V. Ivanishin, Milana Djonovic, Ekaterina A. Romanovskaya-Romanko, Anton N. Kovalenko, Dmitry A. Lioznov, Tatiana G. Zubkova, Svetlana V. Teplykh, Rodion A. Oseshnyuk, Marina A. Stukova, Artur A. Isaev, Igor V. Krasilnikov   +15 more
doaj   +1 more source

Outbreak Patterns of the Novel Avian Influenza (H7N9)

, 2013
The attack of novel avian influenza (H7N9) in east China caused a serious health crisis and public panic. In this paper, we empirically analyze the onset patterns of human cases of the novel avian influenza and observe several spatial and temporal ...
Han, Xiao-Pu, Lou, Jing-Jing, Pan, Ya-Nan   +2 more
core   +1 more source