Results 101 to 110 of about 118,844,745 (215)

Adaptation of H3N2 canine influenza virus to feline cell culture

PLOS ONE, 2019
H3N2 canine influenza viruses are prevalent in Asian and North American countries. During circulation of the viruses in dogs, these viruses are occasionally transmitted to cats. If this canine virus causes an epidemic in cats too, sporadic infections may occur in humans because of the close contact between these companion animals and humans, possibly ...
Haruhiko Kamiki, Hiromichi Matsugo, Hiroho Ishida, Tomoya Kobayashi-Kitamura, Wataru Sekine, Akiko Takenaka-Uema, Shin Murakami, Taisuke Horimoto   +7 more
openaire   +4 more sources

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase [PDF]

, 2010
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Russell, Rupert James Martin, Thomson, Robin J, Dyason, Jeffrey C, von Itzstein, M, Naffakh, Nadia, Nadia Naffakh, Mark von Itzstein, Faith J. Rose, Rameix-Welti, Marie-Anne, Robin J. Thomson, Dyason, JC, Rupert J. M. Russell, van der Werf, S, Russell, Rupert J M, Santosh Rudrawar, Rose, Faith J, Russell, Rupert JM, Kerry, Philip Stephen, Jeffrey C. Dyason, von Itzstein, Mark, Thomson, RJ, Rudrawar, S, Marie-Anne Rameix-Welti, Kerry, Philip S, Rose, FJ, Naffakh, N, Rameix-Welti, MA, Philip S. Kerry, van Der Werf, Sylvie, Rudrawar, Santosh, Sylvie van der Werf   +30 more
core   +1 more source

Low population serum microneutralization antibody titer against the predominating influenza A(H3N2) N121K virus during the severe influenza summer peak of Hong Kong in 2017

Emerging Microbes and Infections, 2018
The 2017 Hong Kong influenza A(H3N2) summer season was unexpectedly severe. However, antigenic characterization of the 2017 circulating A(H3N2) viruses using ferret antisera did not show significant antigenic drift.
Houshun Zhu, Andrew C. Y. Lee, Can Li, Winger W. N. Mak, Yetta Y. Chen, Kwok-Hung Chan, Anna J. X. Zhang, Wai-Fong Fung, Rui-Qi Zhang, Yim-Fong Fung, Rosana W. S. Poon, Joy-Yan Lam, Sidney Tam, Ivan F. N. Hung, Honglin Chen, Kwok-Yung Yuen, Kelvin K. W. To   +16 more
doaj   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

An outbreak of influenza A(H3N2) in Alappuzha district, Kerala, India, in 2011

Journal of Infection in Developing Countries, 2015
Introduction: Influenza is an RNA virus that belongs to the Orthomyxoviridae family. It causes a highly contagious acute respiratory illness, has been recognized since ancient times, and is a major health threat throughout the world.
Sam Peter, Anukumar Balakrishnan, Varsha A Potdar, Mandeep S Chadha, Santhosh M Jadhav   +4 more
doaj   +1 more source

Assessment of pre and postinfection immunity to the hemagglutinin proteins of Influenza A(H1N1)pdm09 and Influenza A(H3N2) in India: a retrospective longitudinal study

Virology Journal
Background Hemagglutinin (HA), one of the main surface glycoproteins of the influenza virus, is essential for viral entry into host cells. Antibodies targeting HA can neutralize the virus, offering protection against infection.
Anup Jayaram, Desmond Cardoso, Arun M.T., Prasad Varamballi, Kavitha Karunakaran, Prachi Malsane, Sudheesh N., Ujwal Shetty, Naren Babu N., Chiranjay Mukhopadhyay, Anitha Jagadesh   +10 more
doaj   +1 more source

VIRUS-SPECIFIC HUMORAL IMMUNE RESPONSE ISOTYPIC STRUCTURE IN ADULT PATIENTS HOSPITALIZED WITH INFLUENZA A

Инфекция и иммунитет, 2016
The aim of this investigation was a comparative analysis of isotypic structure of specific antiviral systemic humoral immune response in hospitalized patients with influenza caused by virus A(H3N2) or A(H1N1), including the A(H1N1)pdm09. Paired acute and
V. Z. Krivitskaya, A. A. Vasilieva, E. M. Voytsekhovskaya, E. R. Petrova, M. M. Pisareva, Zh. V. Buzitskaya, E. A. Elpaeva, A. A. Go, L. V. Voloshchuk, N. I. Lvov, T. D. Smirnova, A. A. Sominina   +11 more
doaj   +1 more source

Seroprevalence of a Novel Influenza A (H3N2) Variant Virus in the Japanese Population

Japanese Journal of Infectious Diseases, 2013
Antibody distribution to a novel swine-origin influenza A (H3N2) variant virus among different age groups in Japan was determined by hemagglutination-inhibition assay. Japanese children in the age group 1-14 years were at a higher risk than those in older age groups.
Kishida, Noriko, Imai, Masaki, Xu, Hong, Taya, Keiko, Fujisaki, Seiichiro, Takashita, Emi, Tashiro, Masato, Odagiri, Takato   +7 more
openaire   +3 more sources

Using Sequence Data To Infer the Antigenicity of Influenza Virus

mBio, 2013
The efficacy of current influenza vaccines requires a close antigenic match between circulating and vaccine strains. As such, timely identification of emerging influenza virus antigenic variants is central to the success of influenza vaccination programs.
Hailiang Sun, Jialiang Yang, Tong Zhang, Li-Ping Long, Kun Jia, Guohua Yang, Richard J. Webby, Xiu-Feng Wan   +7 more
doaj   +1 more source

Selecting vaccine strains for H3N2 human influenza A virus

Meta Gene, 2015
H3N2 human influenza A virus causes epidemics of influenza mainly in the winter season in temperate regions. Since the antigenicity of this virus evolves rapidly, several attempts have been made to predict the major amino acid sequence of hemagglutinin 1 (HA1) in the target season of vaccination.
openaire   +2 more sources