Results 1 to 10 of about 576,499 (346)

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]

, 2014
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Barclay, Wendy S., Bean, Thomas J., Bruce, Christine, Carroll, Miles W., Dimmock, N. J., Dove, Brian K., Dowall, Stuart, Easton, A. J. (Andrew J.), Hallis, Bassam, Marriott, Anthony C., Newman, Edmund, Pearson, Geoff, Plank, Jenna, Rayner, Emma, Ryan, Kathryn A., Silman, Nigel J., Taylor, Irene, Whittaker, Catherine J.   +17 more
core   +14 more sources

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]

, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, A., Hai, R., Hale, B.G., Manicassamy, B., Pena, L., Pérez, D.R., Schmolke, M., Steel, J., Sutton, T., Varga, Z.T.   +9 more
core   +17 more sources

Generation of an Attenuated Chimeric Bat Influenza A Virus Live-Vaccine Prototype

Microbiology Spectrum, 2022
Recurring epizootic influenza A virus (IAV) infections in domestic livestock such as swine and poultry are associated with a substantial economic burden and pose a constant threat to human health.
Wei Ran, Jacob Schön, Kevin Ciminski, Julian Kraft, Susanne Kessler, Sophie Euchner, Donata Hoffmann, Anne Pohlmann, Martin Beer, Martin Schwemmle, Sebastian Giese   +10 more
doaj   +1 more source

Broad-spectrum inhibition of influenza A virus replication by blocking the nuclear export of viral ribonucleoprotein complexes. [PDF]

J Virol
Shen W, Xu J, Chen Z, Wei Y, Wang Q, Wang X, Zhang X, Zhu Q, Xu S.   +8 more
europepmc   +2 more sources

A Systematic Review Analyzing the Prevalence and Circulation of Influenza Viruses in Swine Population Worldwide

Pathogens, 2020
The global anxiety and a significant threat to public health due to the current COVID-19 pandemic reiterate the need for active surveillance for the zoonotic virus diseases of pandemic potential.
Ravendra P. Chauhan, Michelle L. Gordon
doaj   +1 more source

Influenza A Virus: Host–Virus Relationships [PDF]

Viruses, 2020
We are in the midst of a pandemic where the infective agent has been identified, but how it causes mild disease in some and fatally severe disease in other infected individuals remains a mystery [...]
openaire   +3 more sources

Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada

Emerging Infectious Diseases, 2023
Wholly Eurasian highly pathogenic avian influenza H5N1 clade 2.3.4.4b virus was isolated from 2 free-ranging black bears with meningoencephalitis in Quebec, Canada. We found that isolates from both animals had the D701N mutation in the polymerase basic 2
Benjamin T. Jakobek, Yohannes Berhane, Marie-Soleil Nadeau, Carissa Embury-Hyatt, Oliver Lung, Wanhong Xu, Stéphane Lair   +6 more
doaj   +1 more source

Interspecies Transmission of Reassortant Swine Influenza A Virus Containing Genes from Swine Influenza A(H1N1)pdm09 and A(H1N2) Viruses

Emerging Infectious Diseases, 2020
Influenza A(H1N1)pdm09 (pH1N1) virus has become established in swine in the United Kingdom and currently co-circulates with previously enzootic swine influenza A virus (IAV) strains, including avian-like H1N1 and human-like H1N2 viruses.
Helen E. Everett, Bethany Nash, Brandon Z. Londt, Michael D. Kelly, Vivien Coward, Alejandro Nunez, Pauline M. van Diemen, Ian H. Brown, Sharon M. Brookes   +8 more
doaj   +1 more source

Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus

Emerging Infectious Diseases, 2015
Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with ...
Irene Ramos, Mena Mansour, Teddy J. Wohlbold, Megan E. Ermler, Ariana Hirsh, Jonathan A. Runstadler, Ana Fernandez-Sesma, Florian Krammer   +7 more
doaj   +1 more source

Influenza A virus uncoating [PDF]

, 2020
Influenza A virus (IAV) is an enveloped virus of the Orthomyxoviridae with a negative-sense single-stranded RNA genome. During virus cell entry, viral and cellular cues are delivered in a stepwise manner within two distinct cellular compartments-the endosomes and the cytosol.
openaire   +4 more sources