Results 91 to 100 of about 48,268 (246)

Immune protection induced on day 10 following administration of the 2009 A/H1N1 pandemic influenza vaccine. [PDF]

PLoS ONE, 2010
The 2009 swine-origin influenza virus (S-OIV) H1N1 pandemic has caused more than 18,000 deaths worldwide. Vaccines against the 2009 A/H1N1 influenza virus are useful for preventing infection and controlling the pandemic.
Yizhuo Sun, Chao Bian, Ke Xu, Weibin Hu, Tongyan Wang, Jun Cui, Hongqiang Wu, Zhiyang Ling, Yongyong Ji, Guomei Lin, Lin Tian, Yanyan Zhou, Bingnan Li, Guiyu Hu, Ning Yu, Wenqi An, Ruowen Pan, Paul Zhou, Qibin Leng, Zhong Huang, Xiaowei Ma, Bing Sun   +21 more
doaj   +1 more source

Influenza A Virus (H1N1) Infection Induces Ferroptosis to Promote Developmental Injury in Fetal Tissues

Cell Proliferation, EarlyView.
H1N1 infection during pregnancy specifically targets the fetal liver and lungs, triggering immune responses, tissue fibrosis and ferroptosis in parenchymal cells, ultimately leading to adverse pregnancy outcomes, offering insights into managing maternal H1N1 infections and their impact on fetal health.
Yuxi Jiang, Yao Shen, Qiongyin Zhang, Zi Liu, Yuzhen Liu, Jiaojiao Peng, Xuesong Yang, Feng Gao, Xiang‐Hong Ou, Qing‐Yuan Sun, Qiao Zhang, Guang Wang   +11 more
wiley   +1 more source

Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959-2016. [PDF]

, 2019
This study examines the roles of age, period, and cohort in influenza mortality trends over the years 1959-2016 in the United States. First, we use Lexis surfaces based on Serfling models to highlight influenza mortality patterns as well as to identify ...
Acosta, Enrique, Bourbeau, Robert, Dillon, Lisa Y, Earn, David JD, Gagnon, Alain, Hallman, Stacey A, Herring, D Ann, Inwood, Kris, Madrenas, Joaquin, Miller, Matthew S, Ouellette, Nadine   +10 more
core   +1 more source

Determination of Hemagglutinin and Neuraminidase Genetic Variation of Human Influenza A(H1N1)pdm09 Virus Strain Isolated From Deceased Patients in Shiraz, Iran: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims A novel strain of influenza A(H1N1) was first detected in April 2009, resulting in a global pandemic. Alterations in its hemagglutinin (HA) and neuraminidase (NA) proteins can impact the virus's properties, pathogenicity, and response to treatment.
Romina Barkhori, Fahime Edalat, Neda Pirbonyeh, Yasaman Goudarzi, Seyed Younes Hosseini, Afagh Moattari   +5 more
wiley   +1 more source

Influenza A nucleoprotein binding sites for antivirals: current research and future potential [PDF]

, 2014
This document is the Accepted Manuscript version of the following article: Andreas Kukol and Hershna Patel, ‘Influenza A nucleoprotein binding sites for antivirals: current research and future potential’, Future Biology, Vol 9(7): 625-627, July 2014. The
Kukol, A, Kukol, A, Patel, H., Patel, H.
core   +2 more sources

Genetic characterization of influenza virus circulating in Brazilian pigs during 2009 and 2010 reveals a high prevalence of the pandemic H1N1 subtype

Influenza and Other Respiratory Viruses, 2012
Influenza A viruses circulating in pigs in Brazil are still not characterized, and only limited data are available about swine influenza epidemiology in the country.
D. Rajão, A. R. Costa, Bruno S. A. F. Brasil, H. L. Del Puerto, F. G. Oliveira, F. Alves, G. F. Braz, J. Reis, R. Guedes, Z. I. Lobato, R. Leite   +10 more
semanticscholar   +1 more source

MISSEL: a method to identify a large number of small species-specific genomic subsequences and its application to viruses classification [PDF]

, 2016
Continuous improvements in next generation sequencing technologies led to ever-increasing collections of genomic sequences, which have not been easily characterized by biologists, and whose analysis requires huge computational effort.
Babakir Mina, Muhammed, Bertolazzi, Paola, Cella, Eleonora, Ciccozzi, Massimo, Ciotti, Marco, Felici, Giovanni, Fiscon, Giulia, Giovanetti, Marta, Lo Presti, Alessandra, Pierangeli, Alessandra, Weitschek, Emanuel   +10 more
core   +2 more sources

Ratiometric Fluorescence Determination of Avian Influenza a Virus Subtype H1N1 DNA with Functionalized Quantum Dots and Gold Nanoparticles

Analytical Letters, 2022
A new type of ratiometric fluorescence sensor based on DNA functionalized quantum dots (DNA-QDs) and gold nanoparticles (AuNPs) was constructed for sensitive fluorescence determination of the avian influenza A virus subtype H1N1 DNA. Using the nucleic acid strand displacement reaction, the carboxyfluorescein-DNA (FAM-DNA) replaced DNA-QDs on the ...
Ke, Wenmin, Lai, Qizhen, Yang, Yixia, Qian, Jingjing, Ji, Xinghu, He, Zhike   +5 more
openaire   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, Volume 37, Issue 42, October 23, 2025.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Matrix Protein 2 Vaccination and Protection against Influenza Viruses, Including Subtype H5N1

Emerging Infectious Diseases, 2007
Changes in influenza viruses require regular reformulation of strain-specific influenza vaccines. Vaccines based on conserved antigens provide broader protection. Influenza matrix protein 2 (M2) is highly conserved across influenza A subtypes.
Stephen Mark Tompkins, Zi-Shan Zhao, Chia-Yun Lo, Julia A. Misplon, Teresa Liu, Zhiping Ye, Robert J. Hogan, Zhengqi Wu, Kimberly A. Benton, Terrence M. Tumpey, Suzanne L. Epstein   +10 more
doaj   +1 more source