Pulmonary Function and Clinical Manifestations of Patients Infected with Mild Influenza A Virus Subtype H1N1: A One-Year Follow-Up. [PDF]
To investigate the long-term effects of mild H1N1 influenza infection on the pulmonary function of a cohort of patients.Forty-eight patients, all diagnosed with influenza A virus subtype H1N1 in 2009, were retrospectively included in this study.
Wei Liu +3 more
doaj +4 more sources
Influenza Surveillance in the Central African Republic From 2015 to 2018 to Inform Vaccination and Treatment Strategies. [PDF]
ABSTRACT Background Surveillance of influenza infections and virus characterisation are essential to guide prevention strategies. In the Central African Republic (CAR), data on influenza viruses are patchy and poorly documented. Objective To study the clinical, seasonal, genetic and phenotypic characteristics of influenza viruses circulating in the CAR
Komoyo GF +9 more
europepmc +2 more sources
Catastrophic antiphospholipid syndrome (CAPS) induced by influenza A virus subtype H1N1 [PDF]
Catastrophic antiphospholipid syndrome (CAPS) has been associated with several bacterial and viral infections. We presented a case report of a woman who presented to the emergency room, with influenza A virus subtype H1N1 which progressed to CAPS in the course of 17 days. We believe this is the first case that links CAPS with H1N1.
Melonie L, Durkin +3 more
openaire +2 more sources
The role of IL17 and IL17RA polymorphisms in lethal pandemic acute viral pneumonia (Influenza A virus H1N1 subtype) [PDF]
Abstract Background The cytokines play an essential role in acute inflammatory processes, and the IL-17 may be responsible for ambiguous aspects, and the correlation with genetic polymorphisms could improve the search for this critical biomarker. Thus, this study aimed to evaluate the IL-17A and IL-17RA tissue expression
Liberalesso V +15 more
europepmc +3 more sources
2009 Pandemic Influenza A Virus Subtype H1N1 Vaccination in Africa—Successes and Challenges [PDF]
To provide vaccination against infection due to 2009 pandemic influenza A virus subtype H1N1 (A[H1N1]pdm09) to resource-constrained countries with otherwise very little access to the A(H1N1)pdm09 vaccine, the World Health Organization (WHO) coordinated distribution of donated vaccine to selected countries worldwide, including those in Africa.
Richard, Mihigo +7 more
openaire +2 more sources
In silico modification of oseltamivir as neuraminidase inhibitor of influenza A virus subtype H1N1 [PDF]
This research focused on the modification of the functional groups of oseltamivir as neuraminidase inhibitor against influenza A virus subtype H1N1. Interactions of three of the best ligands were evaluated in the hydrated state using molecular dynamics simulation at two different temperatures. The docking result showed that AD3BF2D ligand (N-[(1S,6R)-5-
Tambunan, Usman Sumo Friend +2 more
openaire +2 more sources
Epidemiological and Virological Characterization of 2009 Pandemic Influenza A Virus Subtype H1N1 in Madagascar [PDF]
Madagascar was one of the first African countries to be affected by the 2009 pandemic of influenza A virus subtype H1N1 [A(H1N1)pdm2009] infection. The outbreak started in the capital city, Antananarivo, and then spread throughout the country from October 2009 through February 2010.Specimens from patients presenting with influenza-like illness were ...
Arnaud, Orelle +8 more
openaire +2 more sources
Detection in 2009 of the Swine Origin Influenza A (H1N1) Virus by a Subtyping Microarray [PDF]
A novel H1N1 swine origin influenza A (IAV) virus (S-OIV) was discovered in specimens from two unrelated children in the San Diego area in mid-April 2009 (1, 2). Those samples were positive for IAV but negative for both human H1 and H3 subtypes. The outbreak evolved rapidly, and the World Health Organization (WHO) declared the highest phase 6 worldwide
Qing, Lu +5 more
openaire +2 more sources
Rapid Semiautomated Subtyping of Influenza Virus Species during the 2009 Swine Origin Influenza A H1N1 Virus Epidemic in Milwaukee, Wisconsin [PDF]
ABSTRACT In the spring of 2009, a novel influenza A (H1N1) virus (swine origin influenza virus [S-OIV]) emerged and began causing a large outbreak of illness in Milwaukee, WI. Our group at the Midwest Respiratory Virus Program laboratory developed a semiautomated real-time multiplex reverse transcription-PCR assay (Seasonal), employing the ...
Michael E, Bose +12 more
openaire +2 more sources
Pregnant Women Have Attenuated Innate Interferon Responses to 2009 Pandemic Influenza A Virus Subtype H1N1 [PDF]
Pregnant women are considered to have a high risk for influenza virus infection, although little is known about the biological reasons for this risk. Antiviral immunity is critical during influenza virus infection, and understanding the changes that occur during pregnancy and the effect of vaccination is essential for improving health outcomes for ...
Forbes, Rebecca L. +3 more
openaire +2 more sources

