Results 41 to 50 of about 40,863 (219)

Hemagglutinin sequence conservation guided stem immunogen design from influenza A H3 subtype [PDF]

, 2015
Seasonal epidemics caused by influenza A (H1 and H3 subtypes) and B viruses are a major global health threat. The traditional, trivalent influenza vaccines have limited efficacy because of rapid antigenic evolution of the circulating viruses.
Citron, Michael, Ferrara, Francesca, Flynn, Jessica A, Liang, Xiaoping, Mallajosyula, Vamsee V A, Temperton, Nigel J., Varadarajan, Raghavan   +6 more
core   +4 more sources

Simultaneous Detection of Influenza A, Influenza B, and Respiratory Syncytial Viruses and Subtyping of Influenza A H3N2 Virus and H1N1 (2009) Virus by Multiplex Real-Time PCR [PDF]

Journal of Clinical Microbiology, 2011
ABSTRACT A multiplex real-time PCR assay was developed to simultaneously detect and discriminate influenza A virus subtypes, including novel H1N1 (2009) and seasonal H3N2 virus, influenza B virus, and respiratory syncytial virus (RSV) in a single test tube, with detection sensitivity and specificity of 99% and 100%, respectively, for the four
Yu, Chen, Dawei, Cui, Shufa, Zheng, Shigui, Yang, Jia, Tong, Dagan, Yang, Jian, Fan, Jie, Zhang, Bin, Lou, Xuefen, Li, Xiaoling, Zhuge, Bo, Ye, Baode, Chen, Weilin, Mao, Yajun, Tan, Genyun, Xu, Zhenjin, Chen, Nan, Chen, Lanjuan, Li   +18 more
openaire   +2 more sources

Antibodies of influenza A(H1N1)pdm09 virus in pigs’ sera cross-react with other influenza A virus subtypes. A retrospective epidemiological interpretation of Norway's serosurveillance data from 2009–2017 [PDF]

Epidemiology and Infection, 2020
Abstract Since the incursion of influenza A(H1N1)pdm09 virus in 2009, serosurveillance every year of the Norwegian pig population revealed the herd prevalence for influenza A(H1N1)pdm09 (HIN1pdm09) has stabilised between 40% and 50%. Between 30 September 2009 and 14 September 2017, the Norwegian Veterinary Institute and Norwegian Food Safety ...
Jwee Chiek Er, Bjørn Lium, Tore Framstad   +2 more
openaire   +3 more sources

Generation of a Reassortant Influenza A Subtype H3N2 Virus Expressing Gaussia Luciferase

Viruses, 2019
Reporter influenza A viruses (IAVs) carrying fluorescent or luminescent genes provide a powerful tool for both basic and translational research. Most reporter IAVs are based on the backbone of either subtype H1N1 viruses, A/Puerto Rico/8/1934 (PR8) or A ...
Lin Wang, Qinghua Cui, Xiujuan Zhao, Ping Li, Yanyan Wang, Lijun Rong, Ruikun Du   +6 more
doaj   +1 more source

Impact on pregnancies in south Brazil from the influenza A (H1N1) pandemic: cohort study. [PDF]

PLoS ONE, 2014
INTRODUCTION: The emergence of a new subtype of the influenza virus in 2009 generated interest in the international medical community, the media, and the general population.
André Anjos da Silva, Tani Maria Schilling Ranieri, Fernanda Duarte Torres, Fernanda Sales Luiz Vianna, Graziella Rangel Paniz, Paula Baptista Sanseverino, Paulo Dornelles Picon, Pietro Baptista de Azevedo, Marta Haas Costa, Lavinia Schuler-Faccini, Maria Teresa Vieira Sanseverino   +10 more
doaj   +1 more source

Anticipating the species jump: surveillance for emerging viral threats. [PDF]

, 2012
Zoonotic disease surveillance is typically triggered after animal pathogens have already infected humans. Are there ways to identify high-risk viruses before they emerge in humans? If so, then how and where can identifications be made and by what methods?
Bush, RM, Cobey, S, Flanagan, ML, Glass, GE, Leighton, TJ, Parrish, CR   +5 more
core   +1 more source

Detection and isolation of Influenza A virus subtype H1N1 from a small backyard swine herd in Colorado [PDF]

Journal of Veterinary Diagnostic Investigation, 2013
Influenza A virus subtype H1N1 A(H1N1)pdm09 was first confirmed in pigs in the United States in October 2009. In November 2010, lungs and intestines from 2 York piglets from a small, privately owned herd were submitted to the Colorado State University Veterinary Diagnostic Laboratory. The submitting veterinarian reported rapid weight loss and signs of
Christina B, Weller, Kyran J, Cadmus, E J, Ehrhart, Barbara E, Powers, Kristy L, Pabilonia   +4 more
openaire   +2 more sources

Cardiac complications associated with the influenza viruses A subtype H7N9 or pandemic H1N1 in critically ill patients under intensive care

Brazilian Journal of Infectious Diseases, 2017
Background and objective: The clinical presentations and disease courses of patients hospitalized with either influenza A virus subtype H7N9 (H7N9) or 2009 pandemic H1N1 influenza virus were compared in a recent report, but associated cardiac ...
Jiajia Wang, Hua Xu, Xinjing Yang, Daguo Zhao, Shenglan Liu, Xue Sun, Jian-an Huang, Qiang Guo   +7 more
doaj   +1 more source

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow, Calza, Chan, Cosma, De Jong, Farrohi, Ferrara, Fox, Frank, Fulton, Gross, Halloran, Harmon, Hierholzer, Johansson, Johansson, Kendal, Kilbourne, Montomoli, Okuno, O’Neill, Powers, Probert, Rowe, Schild, Schulman, Schulman, Scott, Sylte, Van Assen, Yewdell   +30 more
core   +3 more sources

Heterovariant Cross-Reactive B-Cell Responses Induced by the 2009 Pandemic Influenza Virus A Subtype H1N1 Vaccine [PDF]

The Journal of Infectious Diseases, 2012
The generation of heterovariant immunity is a highly desirable feature of influenza vaccines. The goal of this study was to compare the heterovariant B-cell response induced by the monovalent inactivated 2009 pandemic influenza A virus subtype H1N1 (A[H1N1]pdm09) vaccine with that induced by the 2009 seasonal trivalent influenza vaccine (sTIV ...
Xiao-Song, He, Sanae, Sasaki, Jane, Baer, Surender, Khurana, Hana, Golding, John J, Treanor, David J, Topham, Mark Y, Sangster, Hong, Jin, Cornelia L, Dekker, Kanta, Subbarao, Harry B, Greenberg   +11 more
openaire   +2 more sources