Simultaneous Detection of Influenza A, Influenza B, and Respiratory Syncytial Viruses and Subtyping of Influenza A H3N2 Virus and H1N1 (2009) Virus by Multiplex Real-Time PCR [PDF]
ABSTRACT A multiplex real-time PCR assay was developed to simultaneously detect and discriminate influenza A virus subtypes, including novel H1N1 (2009) and seasonal H3N2 virus, influenza B virus, and respiratory syncytial virus (RSV) in a single test tube, with detection sensitivity and specificity of 99% and 100%, respectively, for the four
Yu, Chen +18 more
openaire +2 more sources
Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza [PDF]
Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine Methods: We ...
Harald Bias +15 more
core +1 more source
Generation of a Reassortant Influenza A Subtype H3N2 Virus Expressing Gaussia Luciferase
Reporter influenza A viruses (IAVs) carrying fluorescent or luminescent genes provide a powerful tool for both basic and translational research. Most reporter IAVs are based on the backbone of either subtype H1N1 viruses, A/Puerto Rico/8/1934 (PR8) or A ...
Lin Wang +6 more
doaj +1 more source
Estimating Influenza-associated Mortality in Korea: The 2009-2016 Seasons [PDF]
Objectives Estimating influenza-associated mortality is important since seasonal influenza affects persons of all ages, causing severe illness or death.
Kwan Hong, Sangho Sohn, Byung Chul Chun
doaj +1 more source
Abstract Background Inbred mice have several advantages, including genetic similarity to humans, a well-established gene manipulation system, and strong tolerance to inbreeding. However, inbred mice derived from a limited genetic pool have a small genetic diversity.
Hajin Nam +8 more
openaire +3 more sources
Estimation of outbreak severity and transmissibility : influenza A(H1N1)pdm09 in households [PDF]
When an outbreak of a novel pathogen occurs, some of the most pressing questions from a public-health point of view relate to its transmissibility, and the probabilities of different clinical outcomes following infection, to allow an informed response ...
Inglis, N. +38 more
core +2 more sources
Background and objective: The clinical presentations and disease courses of patients hospitalized with either influenza A virus subtype H7N9 (H7N9) or 2009 pandemic H1N1 influenza virus were compared in a recent report, but associated cardiac ...
Jiajia Wang +7 more
doaj +1 more source
Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K. +35 more
core +1 more source
A Historical Perspective of Influenza A(H1N2) Virus
The emergence and transition to pandemic status of the influenza A(H1N1)A(H1N1)pdm09) virus in 2009 illustrated the potential for previously circulating human viruses to re-emerge in humans and cause a pandemic after decades of circulating among animals.
Naomi Komadina +3 more
doaj +1 more source
Unusual association of ST-T abnormalities, myocarditis and cardiomyopathy with H1N1 influenza in pregnancy: two case reports and review of the literature [PDF]
Introduction Myocarditis is rarely reported as an extra-pulmonary manifestation of influenza while pregnancy is a rare cause of cardiomyopathy. Pregnancy was identified as a major risk factor for increased mortality and morbidity due to H1N1 influenza in
Chakravorty, I +8 more
core +2 more sources

