Results 121 to 130 of about 18,665 (167)

Rescue of H5N1 subtypeavian influenza A viruslethal to mice

Chinese Journal of Agricultural Biotechnology, 2007
AbstractAvian influenza virus is acquiring the ability to cross the species barrier between birds and mammals. However, the genetic mechanism of this ability is not well known. We successfully rescued aninfluenza A virusA/Chicken/Guangdong/03 (H5N1), which is highly pathogenic to both SPF chickens and BALB/c mice, by plasmid-based reverse genetics. The
Pan Wei-Qi, Liu Ming, Zhang Yun, Liu Chun-Guo, Yang Tao, Li Jing-Peng   +5 more
openaire   +1 more source

Lysiphyllum strychnifolium (Craib) A. Schmitz extract, a novel neuraminidase inhibitor of avian influenza virus subtype H5N1

Journal of Herbal Medicine, 2020
Abstract The leaves and stems of Lysiphyllum strychnifolium (Craib) A. Schmitz (Fabaceae family) have been traditionally used in Thailand for detoxification and to treat pesticide poisoning in humans. To uncover novel uses of L.strychnifolium, the possible antiviral properties against avian influenza virus A, strain H5N1, were explored in this study.
Sophida Sukprasert, Kanoktip Pansuksan, Kusuma Sriyakul   +2 more
openaire   +1 more source

Economic loss in poultry farms affected with highly pathogenic avian influenza A virus subtype H5N1 and low pathogenic avian influenza A virus subtype H9N2 in Chattogram, Bangladesh

Bangladesh Journal of Veterinary and Animal Sciences, 2020
Depending on the degree of pathogenicity in chickens, avian influenza virus (AIV) are divided into highly pathogenic (HPAI) or low pathogenic AI (LPAI) viruses. Typically, high morbidity accompanied by high and rapidly escalating unexplained mortality is associated with a HPAI virus.
Ripatun Nahar Ripa, Tridip Das, Himel Barua, Md. Inkeyas Uddin, Md. Reajul Haque, Md. Masuduzzaman, A.K.M Saifuddin, Paritosh Kumar Biswas   +7 more
openaire   +1 more source

Understanding of Drug-Target Interactions: A case Study in Influenza Virus A Subtype H5N1

AIP Conference Proceedings, 2007
This study aims at gaining insight into molecular mechanisms of action of three drug targets of the life cycle of influenza virus A subtype H5N1, namely Hemagglutinin (H5), Neuraminidase (N1) and M2 ion channel (M2), using molecular mechanics and molecular dynamics techniques.
Thanyada Rungrotmongkol, Maturos Malaisree, Panita Decha, Chittima Laohpongspaisan, Ornjira Aruksakunwong, Pathumwadee Intharathep, Somsak Pianwanit, Pornthep Sompornpisut, Vudhichai Parasuk, Eugene Megnassan, Vladimir Frecer, Stanislav Miertus, Supot Hannongbua, Theodore E. Simos, George Maroulis   +14 more
openaire   +1 more source

Characterisation and haemagglutinin gene epitope mapping of a variant strain of H5N1 subtype avian influenza virus

Veterinary Microbiology, 2013
H5N1 avian influenza virus (AIV) undergoes rapid evolution, and its antigenicity needs to be constantly evaluated in order to update the vaccine strain. In this report, a clade 7.2 AIV isolate named A/Chicken/Huadong/4/2008 (DT) is identified. Antigenic analysis revealed that DT had a significant low cross-reactive HI titre with antiserum against a ...
Yanfang, Li, Xiaojian, Zhang, Quangang, Xu, Qiang, Fu, Yinbiao, Zhu, Sujuan, Chen, Daxin, Peng, Xiufan, Liu   +7 more
openaire   +2 more sources

Simultaneous detection of influenza virus type B and influenza A virus subtypes H1N1, H3N2, and H5N1 using multiplex real-time RT-PCR

Applied Microbiology and Biotechnology, 2011
Use of multiplex real-time reverse transcription polymerase chain reaction (RT-PCR) for the simultaneous detection of influenza type B virus and influenza A virus subtypes H5N1, H3N2, and H1N1 has been described. The method exhibited a high specificity and sensitivity of approximately 10(1)-10(2) copies per microliter or 10(-3)-10(-2) TCID50/L for each
Fang, Shisong, Li, Jianxiong, Cheng, Xiaowen, Zhao, Cunyou, Wang, Ting, Lv, Xing, Wang, Xin, Wu, Chunli, Zhang, Renli, Cheng, Jinquan, Hong, Xue, Yu, Muhua   +11 more
openaire   +3 more sources

Single-Step Multiplex Reverse Transcription–Polymerase Chain Reaction (RT-PCR) for Influenza A Virus Subtype H5N1 Detection

Viral Immunology, 2004
Influenza A virus subtype H5N1 causes a rapidly fatal systemic disease in domestic poultry and spreads directly from poultry to humans. The aim of this study was to develop a rapid, cost-saving and effective method for influenza A virus subtype H5N1 detection.
Sunchai, Payungporn, Piraya, Phakdeewirot, Salin, Chutinimitkul, Apiradee, Theamboonlers, Juthatip, Keawcharoen, Kanisak, Oraveerakul, Alongkorn, Amonsin, Yong, Poovorawan   +7 more
openaire   +2 more sources

Prepandemic Influenza Vaccine H5N1 (Split Virion, Inactivated, Adjuvanted) [Prepandrix™]

BioDrugs, 2008
Although rare, influenza pandemics are a recurrent event, and influenza A/H5N1 is generally considered to be the most likely causative agent of the next pandemic. Vaccines are widely considered to be the first line of defense for protecting populations in advance of an influenza pandemic.
Natalie J, Carter, Greg L, Plosker
openaire   +2 more sources

Encephalitis in a Stone Marten (Martes foina) after Natural Infection with Highly Pathogenic Avian Influenza Virus Subtype H5N1

Journal of Comparative Pathology, 2007
Recent outbreaks of disease in different avian species, caused by the highly pathogenic avian influenza virus (HPAIV), have involved infection by subtype H5N1 of the virus. This virus has also crossed species barriers and infected felines and humans.
R, Klopfleisch, P U, Wolf, C, Wolf, T, Harder, E, Starick, M, Niebuhr, T C, Mettenleiter, J P, Teifke   +7 more
openaire   +2 more sources

Human single-chain antibodies that neutralize homologous and heterologous strains and clades of influenza a virus subtype H5N1

Antiviral Therapy, 2008
Background Human antibodies that interfere with the biological activity of haemagglutinins (HAs) of influenza viruses have high potential as an antiviral agent. Methods Human single-chain antibody fragments (HuScFv) to recombinant and native HAs of the influenza virus H5N1 subtype were produced using a human antibody phage display library with the ...
Santi, Maneewatch, Jeeraphong, Thanongsaksrikul, Thaweesak, Songserm, Kanyarat, Thueng-In, Kasem, Kulkeaw, Umaporn, Thathaisong, Potjanee, Srimanote, Pongsri, Tongtawe, Pramuan, Tapchaisri, Wanpen, Chaicumpa   +9 more
openaire   +2 more sources