Results 211 to 220 of about 31,937 (255)

Dynamic Behavior of Avian Influenza A Virus Neuraminidase Subtype H5N1 in Complex with Oseltamivir, Zanamivir, Peramivir, and Their Phosphonate Analogues

Journal of Chemical Information and Modeling, 2009
The outbreak of avian influenza A subtype H5N1 virus has raised a global concern for both animal as well as human health. Recently, drug resistance in H5N1 infections has been widely reported due to neuraminidase mutations. Consequently, the understanding of inhibitor-neuraminidase interactions at the molecular level represents the main goal of our ...
Thanyarat Udommaneethanakit, T. Rungrotmongkol, U. Bren, V. Frecer, S. Miertus   +4 more
semanticscholar   +3 more sources

Prepandemic Influenza Vaccine H5N1 (Split Virion, Inactivated, Adjuvanted) [Prepandrix™]

BioDrugs, 2008
Although rare, influenza pandemics are a recurrent event, and influenza A/H5N1 is generally considered to be the most likely causative agent of the next pandemic. Vaccines are widely considered to be the first line of defense for protecting populations in advance of an influenza pandemic.
Natalie J, Carter, Greg L, Plosker
openaire   +2 more sources

Antibodies to Influenza A(H5N1) Virus in Hunting Dogs Retrieving Wild Fowl, Washington, USA

Emerging Infectious Diseases
We detected antibodies to H5 and N1 subtype influenza A viruses in 4/194 (2%) dogs from Washington, USA, that hunted or engaged in hunt tests and training with wild birds. Historical data provided by dog owners showed seropositive dogs had high levels of
Justin D. Brown, Adam Black, Katherine H. Haman, D. Diel, Vickie E. Ramirez, Rachel S. Ziejka, Hannah T Fenelon, Peter M. Rabinowitz, Lila Stevens, R. Poulson, D. Stallknecht   +10 more
semanticscholar   +1 more source

Encephalitis in a Stone Marten (Martes foina) after Natural Infection with Highly Pathogenic Avian Influenza Virus Subtype H5N1

Journal of Comparative Pathology, 2007
Recent outbreaks of disease in different avian species, caused by the highly pathogenic avian influenza virus (HPAIV), have involved infection by subtype H5N1 of the virus. This virus has also crossed species barriers and infected felines and humans.
R, Klopfleisch, P U, Wolf, C, Wolf, T, Harder, E, Starick, M, Niebuhr, T C, Mettenleiter, J P, Teifke   +7 more
openaire   +2 more sources

Isolation and characterization of influenza A virus (subtype H5N1) that caused the first highly pathogenic avian influenza outbreak in chicken in Bhutan

Veterinary Microbiology, 2012
We characterized Influenza A/H5N1 virus that caused the first outbreak of highly pathogenic avian influenza (HPAI) in chickens in Bhutan in 2010. The virus was highly virulent to chicken, killing them within two days of the experimental inoculation with an intravenous pathogenicity index (IVPI) of 2.88.
S C, Dubey, N, Dahal, S, Nagarajan, C, Tosh, H V, Murugkar, K, Rinzin, B, Sharma, R, Jain, M, Katare, S, Patil, R, Khandia, Z, Syed, S, Tripathi, P, Behera, M, Kumar, D D, Kulkarni, Lal, Krishna   +16 more
openaire   +2 more sources

Rapid Detection of Avian Influenza Virus A and Subtype H5N1 by Single Step Multiplex Reverse Transcription-polymerase Chain Reaction

Virus Genes, 2006
Outbreaks of H5N1 highly pathogenic avian influenza (HPAI) virus caused great economic losses to the poultry industry and resulted in human deaths in Thailand and Viet Nam in 2004. Rapid typing and subtyping of H5N1 viruses, especially from clinical specimens, are desirable for taking prompt control measures to prevent the spread of the disease.
Hui-Ling, Wei, Gui-Rong, Bai, Aaron S, Mweene, Ying-Chun, Zhou, Yan-Long, Cong, Juan, Pu, Shuai, Wang, Hiroshi, Kida, Jin-Hua, Liu   +8 more
openaire   +2 more sources

Comparison of neuraminidase activity of influenza A virus subtype H5N1 and H1N1 using reverse genetics virus.

The Southeast Asian journal of tropical medicine and public health, 2010
Neuraminidase (NA) is an envelope surface glycoprotein of influenza A viruses. It cleaves alpha-(2,3) or alpha-(2,6) glycosidic linkage between a terminal sialic acid residue of the host cell receptor and hemagglutinin of the viral envelope, thus releasing viral progeny from the infected cell.
Anchalee, Rawangkhan, Donruedee, Sanguansermsri, Narutchala, Suwannakhon, Sutatip, Pongcharoen, Purinthra, Pensuwan, Chanpen, Chamnanpood, Pornchai, Chamnanpood, Phanchana, Sanguansermsri   +7 more
openaire   +1 more source

Development of a recombinant fowlpox virus vector-based vaccine of H5N1 subtype avian influenza.

Developments in biologicals, 2006
The genetic stability of the recombinant fowlpox virus (named rFPV-HA-NA) was confirmed by serial passage on chicken embryo fibroblast (CEF) cells. The immune efficacy, safety, the minimum immunising dose, the time of immunity induced and the immune duration of the vector-based vaccine was evaluated in specific-pathogen-free (SPF) chickens.
C, Qiao, K, Yu, Y, Jiang, C, Li, G, Tian, X, Wang, H, Chen   +6 more
openaire   +1 more source

Comparative study of the hemagglutinin and neuraminidase genes of influenza A virus H3N2, H9N2, and H5N1 subtypes using bioinformatics techniques

Canadian Journal of Microbiology, 2007
To investigate the genomic patterns of influenza A virus subtypes, such as H3N2, H9N2, and H5N1, we collected 1842 sequences of the hemagglutinin and neuraminidase genes from the NCBI database and parsed them into 7 categories: accession number, host species, sampling year, country, subtype, gene name, and sequence.
Insung, Ahn, Hyeon S, Son
openaire   +2 more sources

Prokaryotic expression and characterization of avian influenza A virus M2 gene as a candidate for universal recombinant vaccine against influenza A subtypes; specially H5N1 and H9N2

Molecular Biology Reports, 2009
The conserved M2 protein of influenza A virus is considered as a promising candidate target for a broad-spectrum, recombinant influenza A vaccine. In the present study, the open reading frame (ORF) of avian influenza A/chicken/Iran/101/1998 (H9N2) M2 gene was amplified then cloned in pAED4, prokaryotic expression vector. M2 protein was produced through
Seyyed Mahmoud, Ebrahimi, Majid, Tebianian, Khosrow, Aghaiypour, Hassan, Nili, Ali, Mirjalili   +4 more
openaire   +2 more sources