Results 101 to 110 of about 947,263 (392)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Influenza virus in human exhaled breath: an observational study. [PDF]

PLoS ONE, 2008
Recent studies suggest that humans exhale fine particles during tidal breathing but little is known of their composition, particularly during infection.We conducted a study of influenza infected patients to characterize influenza virus and particle ...
Patricia Fabian, James J McDevitt, Wesley H DeHaan, Rita O P Fung, Benjamin J Cowling, Kwok Hung Chan, Gabriel M Leung, Donald K Milton   +7 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Evaluation of recombinant influenza virus-simian immunodeficiency virus vaccines in macaques [PDF]

, 2009
There is an urgent need for human immunodeficiency virus (HIV) vaccines that induce robust mucosal immunity. Influenza A viruses (both H1N1 and H3N2) were engineered to express simian immunodeficiency virus (SIV) CD8 T-cell epitopes and evaluated ...
Alcantara, Sheilajen, De Rose, Robert, Doherty, Peter C., Hurt, Aeron, Kent, Stephen J., Laurie, Karen, Loh, Liyen, Moffat, Jessica M., Reece, Jeanette C., Sexton, Amy, Stambas, John, Turner, Stephen J.   +11 more
core   +2 more sources

Determination of cold-adapted influenza virus (Orthomyxoviridae: Alphainfluenzavirus) polymerase activity by the minigenome method with a fluorescent protein

Вопросы вирусологии, 2023
Introduction. Polymerase proteins PB1 and PB2 determine the cold-adapted phenotype of the influenza virus A/Krasnodar/101/35/59 (H2N2), as was shown earlier. Objective.
Pavel A. Ivanov, Aleksandr V. Lyashko, Vladimir Y. Kost, Natalia F. Lomakina, Artyom A. Rtishchev, Nataliya I. Bunkova, Tatiana A. Timofeeva, Marina A. Balanova, Stepan A. Ionov, Dmitry V. Gorikov, Stanislav G. Markushin   +10 more
doaj   +1 more source

Characterization of a Novel Influenza A Virus Hemagglutinin Subtype (H16) Obtained from Black-Headed Gulls

Journal of Virology, 2005
In wild aquatic birds and poultry around the world, influenza A viruses carrying 15 antigenic subtypes of hemagglutinin (HA) and 9 antigenic subtypes of neuraminidase (NA) have been described.
R. Fouchier, V. Munster, A. Wallensten, T. Bestebroer, S. Herfst, Derek J. Smith, G. Rimmelzwaan, B. Olsen, A. Osterhaus   +8 more
semanticscholar   +1 more source

Influenza virus infections [PDF]

Postgraduate Medical Journal, 1973
Summary Ninety-six strains of influenza A and 113 influenza B were found in the two MRC/PHLS surveys. In the general practitioner survey the majority of strains were isolated from cases diagnosed as influenza but in hospital most came from cases diagnosed as having other respiratory infections.
openaire   +3 more sources

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Spread of Canine Influenza A(H3N2) Virus, United States

Emerging Infectious Diseases, 2017
A canine influenza A(H3N2) virus emerged in the United States in February–March 2015, causing respiratory disease in dogs. The virus had previously been circulating among dogs in Asia, where it originated through the transfer of an avian-origin influenza
Ian E. H. Voorhees, A. Glaser, K. Toohey-Kurth, Sandra P. Newbury, B. Dalziel, E. Dubovi, K. Poulsen, C. Leutenegger, Katriina Willgert, Laura Brisbane-Cohen, Jill Richardson-Lopez, E. Holmes, C. Parrish   +12 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source