Results 101 to 110 of about 3,100,016 (354)

Predicting Fixation Tendencies of the H3N2 Influenza Virus by Free Energy Calculation [PDF]

open access: yesJ. Chem. Theory Comput. 7 (2011) 1259-1272, 2012
Influenza virus evolves to escape from immune system antibodies that bind to it. We used free energy calculations with Einstein crystals as reference states to calculate the difference of antibody binding free energy ($\Delta\Delta G$) induced by amino acid substitution at each position in epitope B of the H3N2 influenza hemagglutinin, the key target ...
arxiv  

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

Results of Epidemiological Monitoring Bird Flu in Kyrgyz Republic

open access: yesЭпидемиология и вакцинопрофилактика, 2016
The results of the study with modern molecular genetic research methods the circulation in the Kyrgyzstan territory avian flu virus in waterfowl and humans.
K. T. Kasymbekova   +3 more
doaj   +1 more source

Electrospinning and Nanofiber Technology: Fundamentals, Innovations, and Applications

open access: yesAdvanced Materials, EarlyView.
This review explores electrospinning fundamentals, methods for synthesizing polymer, metal oxide, carbon, and composite nanofibers, and advancements in fiber architectures like porous, core–shell, and aligned structures. It highlights applications in functional membranes, sensors, energy systems, and catalyst design while addressing future ...
Yujang Cho   +5 more
wiley   +1 more source

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

open access: yesAdvanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash   +9 more
wiley   +1 more source

US healthcare costs attributable to type A and type B influenza

open access: yesHuman Vaccines & Immunotherapeutics, 2017
While the overall healthcare burden of seasonal influenza in the United States (US) has been well characterized, the proportion of influenza burden attributable to type A and type B illness warrants further elucidation.
Songkai Yan   +2 more
doaj   +1 more source

Early pathogen replacement in a model of Influenza and Respiratory Syncytial Virus with partial vaccination. A computational study [PDF]

open access: yesarXiv, 2017
In this paper, we carry out a computational study using the spectral decomposition of the fluctuations of a two-pathogen epidemic model around its deterministic attractor, i.e., steady state or limit cycle, to examine the role of partial vaccination and between-host pathogen interaction on early pathogen replacement during seasonal epidemics of ...
arxiv  

Electrical Monitoring of Vibrio vulnificus–Host Cell Membrane Interactions in Simple and Complex Matrices

open access: yesAdvanced Materials Interfaces, EarlyView.
Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler   +4 more
wiley   +1 more source

The role of influenza neuraminidase transmembrane domain on budding and virus morphology [PDF]

open access: yes, 2014
Influenza A virus neuraminidase (NA), a type II transmembrane glycoprotein plays a role in the cleavage of sialic acids and facilitating the release of mature virions from the surface of infected cells. NA has also previously been shown to play a role in
Roddy, Scott, Edward
core  

RIG-I signaling Is essential for influenza B virus-induced rapid interferon gene expression [PDF]

open access: yes, 2015
Influenza B virus causes annual epidemics and, along with influenza A virus, accounts for substantial disease and economic burden throughout the world.
Diamond, Michael S   +6 more
core   +2 more sources

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