Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash+9 more
wiley +1 more source
Targeting Hemagglutinin: Approaches for Broad Protection against the Influenza A Virus
Influenza A viruses are dynamically epidemic and genetically diverse. Due to the antigenic drift and shift of the virus, seasonal vaccines are required to be reformulated annually to match with current circulating strains.
Yun Zhang+5 more
doaj +1 more source
STUDIES ON INFLUENZA IN THE PANDEMIC OF 1957-1958. III. ISOLATION OF INFLUENZA A (ASIAN STRAIN) VIRUSES FROM INFLUENZA PATIENTS WITH PULMONARY COMPLICATIONS. DETAILS OF VIRUS ISOLATION AND CHARACTERIZATION OF ISOLATES, WITH QUANTITATIVE COMPARISON OF ISOLATION METHODS* [PDF]
Edwin D. Kilbourne
openalex +1 more source
Avian Influenza A(H10N7) Virus–Associated Mass Deaths among Harbor Seals
To the Editor: Avian influenza A viruses occasionally cross the species barrier; influenza A(H5N1) virus and the recently emerged influenza A(H7N9) virus are prime examples of bird-to-human transmission (1,2).
R. Bodewes+11 more
semanticscholar +1 more source
Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler+4 more
wiley +1 more source
Chicken cyclophilin A is an inhibitory factor to influenza virus replication
Background The importance of enhancing influenza resistance in domestic flocks is quite clear both scientifically and economically. Chicken is very susceptible to influenza virus.
Sun Lei+4 more
doaj +1 more source
Studies on air-borne virus infections: I. Experimental technique and preliminary observations on influenza and infectious ectromelia [PDF]
D. G. ff. Edward+2 more
openalex +1 more source
Reassortant Highly Pathogenic Influenza A(H5N6) Virus in Laos
In March 2014, avian influenza in poultry in Laos was caused by an emergent influenza A(H5N6) virus. Genetic analysis indicated that the virus had originated from reassortment of influenza A(H5N1) clade 2.3.2.1b, variant clade 2.3.4, and influenza A(H6N6)
F. Wong+17 more
semanticscholar +1 more source
Photonic Crystal Enhanced Microscopy on a 2D Photonic Crystal Surface
This work demonstrates the design, fabrication, and the first‐time test of a 2D photonic crystal surface for photonic resonator absorption microscopy. The designed surface uniformly enhances electromagnetic near fields, achieving > 100% improved detecting uniformity for surface‐captured AuNPs from a blocking biosensor assay aimed for detecting SARS‐CoV‐
Weinan Liu+5 more
wiley +1 more source
Acute Encephalopathy Associated with Influenza A Infection in Adults
We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence ...
Nelson Lee+10 more
doaj +1 more source