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Integrating influenza antigenic dynamics with molecular evolution. [PDF]
Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains ...
Abed+83 more
core +5 more sources
Canalization of the evolutionary trajectory of the human influenza virus [PDF]
Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. Antigenic evolution occurs in the context of a two-dimensional 'antigenic map', while genetic evolution shows a characteristic ladder-like ...
A Kucharski+43 more
core +6 more sources
Influenza Virus in Human Exhaled Breath: An Observational Study [PDF]
Background: Recent studies suggest that humans exhale fine particles during tidal breathing but little is known of their composition, particularly during infection.
Chan, Kwok Hung+8 more
core +3 more sources
Every year, especially during the cold season, many people catch an acute respiratory disease, namely flu. It is easy to catch this disease; therefore, it spreads very rapidly and often becomes an epidemic or a global pandemic. Airway inflammation and other body ailments, which form in a very short period, torment the patient several weeks. After that,
Juozapaitis, Mindaugas+1 more
openaire +5 more sources
Influenza Virus and Vaccination [PDF]
Influenza virus infections represent a serious public health problem causing contagious respiratory disease and substantial morbidity and mortality in humans, resulting in a considerable economic burden worldwide. Notably, the number of deaths due to influenza exceeds that of any other known pathogen.
Aitor Nogales, Marta L. DeDiego
openaire +6 more sources
Influenza Virus Infections in Cats [PDF]
In the past, cats were considered resistant to influenza. Today, we know that they are susceptible to some influenza A viruses (IAVs) originating in other species. Usually, the outcome is only subclinical infection or a mild fever. However, outbreaks of feline disease caused by canine H3N2 IAV with fever, tachypnoea, sneezing, coughing, dyspnoea and ...
Frymus, Tadeusz+15 more
openaire +12 more sources
Generation of an Attenuated Chimeric Bat Influenza A Virus Live-Vaccine Prototype
Recurring epizootic influenza A virus (IAV) infections in domestic livestock such as swine and poultry are associated with a substantial economic burden and pose a constant threat to human health.
Wei Ran+10 more
doaj +1 more source
Viroporins in the Influenza Virus [PDF]
Influenza is a highly contagious virus that causes seasonal epidemics and unpredictable pandemics. Four influenza virus types have been identified to date: A, B, C and D, with only A–C known to infect humans. Influenza A and B viruses are responsible for seasonal influenza epidemics in humans and are responsible for up to a billion flu infections ...
Janet To, Jaume Torres
openaire +4 more sources
The global anxiety and a significant threat to public health due to the current COVID-19 pandemic reiterate the need for active surveillance for the zoonotic virus diseases of pandemic potential.
Ravendra P. Chauhan, Michelle L. Gordon
doaj +1 more source
Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada
Wholly Eurasian highly pathogenic avian influenza H5N1 clade 2.3.4.4b virus was isolated from 2 free-ranging black bears with meningoencephalitis in Quebec, Canada. We found that isolates from both animals had the D701N mutation in the polymerase basic 2
Benjamin T. Jakobek+6 more
doaj +1 more source